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ATP22 Atp22p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851952, updated on 2-Nov-2024

Summary

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Official Symbol
ATP22
Official Full Name
Atp22p
Primary source
SGD:S000002758
Locus tag
YDR350C
See related
AllianceGenome:SGD:S000002758; FungiDB:YDR350C; VEuPathDB:YDR350C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
TCM10
Summary
Enables translation regulator activity. Involved in positive regulation of mitochondrial translation and proton-transporting two-sector ATPase complex assembly. Located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ATP22 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (1176120..1178174, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene putative aspartic endopeptidase Neighboring gene tRNA-Met Neighboring gene Sbe2p Neighboring gene Ypq2p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ATP22, a nuclear gene required for expression of the F0 sector of mitochondrial ATPase in Saccharomyces cerevisiae. Helfenbein KG, et al. J Biol Chem, 2003 May 30. PMID 12646576
  2. [Accumulation of inorganic polyphosphates of different fractions in mutant Saccharomyces cerevisiae with an error in synthesis ATP of mitochondria]. Tomashevskiĭ AA, et al. Mikrobiologiia, 2010 Jan-Feb. PMID 20411658
  3. The Saccharomyces cerevisiae ATP22 gene codes for the mitochondrial ATPase subunit 6-specific translation factor. Zeng X, et al. Genetics, 2007 Jan. PMID 17110482, Free PMC Article
  4. F1-dependent translation of mitochondrially encoded Atp6p and Atp8p subunits of yeast ATP synthase. Rak M, et al. Proc Natl Acad Sci U S A, 2009 Nov 3. PMID 19841266, Free PMC Article
  5. Spatial orchestration of mitochondrial translation and OXPHOS complex assembly. Stoldt S, et al. Nat Cell Biol, 2018 May. PMID 29662179

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mitochondrial ATP synthase of Saccharomyces cerevisiae plays role in accumulation of inorganic polyphosphates during fungus growth on culture media with glucose.
    Title: [Accumulation of inorganic polyphosphates of different fractions in mutant Saccharomyces cerevisiae with an error in synthesis ATP of mitochondria].
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables translation regulator activity IEA
Inferred from Electronic Annotation
more info
  
enables translation regulator activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables translation regulator activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of mitochondrial translation IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in positive regulation of mitochondrial translation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in proton-transporting two-sector ATPase complex assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Atp22p
NP_010637.4
  • Specific translational activator for the mitochondrial ATP6 mRNA; Atp6p encodes a subunit of F1F0 ATP synthase; localized to the mitochondrial inner membrane

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    1176120..1178174 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180658.4 → NP_010637.4  TPA: Atp22p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010637.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A6ZYV0, B5VGN1, C8Z5R1, D6VSY0, P50273
    UniProtKB/TrEMBL
    N1P700
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P50273.1

Gene LinkOut

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