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CSN9 Csn9p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851759, updated on 18-Sep-2024

Summary

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Official Symbol
CSN9
Official Full Name
Csn9p
Primary source
SGD:S000002586
Locus tag
YDR179C
See related
AllianceGenome:SGD:S000002586; FungiDB:YDR179C; VEuPathDB:YDR179C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion and protein deneddylation. Part of COP9 signalosome. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See CSN9 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (818708..819196, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene E2 ubiquitin-conjugating protein UBC1 Neighboring gene succinate dehydrogenase membrane anchor subunit SDH4 Neighboring gene Nvj3p Neighboring gene cohesin-loading factor complex subunit SCC2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Saccharomyces cerevisiae as a Toolkit for COP9 Signalosome Research. Harshuk-Shabso D, et al. Biomolecules, 2021 Mar 25. PMID 33806190, Free PMC Article
  2. The COP9 signalosome is involved in the regulation of lipid metabolism and of transition metals uptake in Saccharomyces cerevisiae. Licursi V, et al. FEBS J, 2014 Jan. PMID 24164706
  3. The COP9 signalosome-like complex in S. cerevisiae and links to other PCI complexes. Maytal-Kivity V, et al. Int J Biochem Cell Biol, 2003 May. PMID 12672462
  4. COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae. Maytal-Kivity V, et al. EMBO Rep, 2002 Dec. PMID 12446563, Free PMC Article
  5. Conservation of the COP9/signalosome in budding yeast. Wee S, et al. BMC Genet, 2002 Aug 20. PMID 12186635, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in cellular response to pheromone IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in conjugation with cellular fusion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cytoplasmic translational initiation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein deneddylation IEA
Inferred from Electronic Annotation
more info
  
involved_in protein deneddylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of COP9 signalosome IDA
Inferred from Direct Assay
more info
 PubMed 
part_of COP9 signalosome IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of eukaryotic translation initiation factor 3 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Csn9p
NP_010464.1
  • Subunit of the Cop9 signalosome; Cop9 signalosome is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    818708..819196 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180486.1 → NP_010464.1  TPA: Csn9p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010464.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VSG1, Q03981
    UniProtKB/TrEMBL
    A6ZYD7, B3LGA4, C7GN18, C8Z592, G2WAS7, N1PAE9
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q03981.1

Gene LinkOut

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