U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

TAF10 Taf10p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851745, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
TAF10
Official Full Name
Taf10p
Primary source
SGD:S000002574
Locus tag
YDR167W
See related
AllianceGenome:SGD:S000002574; FungiDB:YDR167W; VEuPathDB:YDR167W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
TAF23; TAF25
Summary
Enables chromatin binding activity and molecular adaptor activity. Involved in RNA polymerase II preinitiation complex assembly and chromatin organization. Part of SAGA complex; SLIK (SAGA-like) complex; and transcription factor TFIID complex. Orthologous to human TAF10 (TATA-box binding protein associated factor 10). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See TAF10 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (789449..790069)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Trm82p Neighboring gene exocyst subunit SEC5 Neighboring gene Cdc37p Neighboring gene Stb3p

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Improvement of oxidative stress tolerance in Saccharomyces cerevisiae through global transcription machinery engineering. Zhao H, et al. J Ind Microbiol Biotechnol, 2014 May. PMID 24633583
  2. Engineering yeast transcription machinery for improved ethanol tolerance and production. Alper H, et al. Science, 2006 Dec 8. PMID 17158319
  3. Activator-mediated recruitment of the RNA polymerase II machinery is the predominant mechanism for transcriptional activation in yeast. Keaveney M, et al. Mol Cell, 1998 May. PMID 9660975
  4. TAF25p, a non-histone-like subunit of TFIID and SAGA complexes, is essential for total mRNA gene transcription in vivo. Sanders SL, et al. J Biol Chem, 1999 Jul 2. PMID 10383379
  5. Validation of reference genes for quantitative expression analysis by real-time RT-PCR in Saccharomyces cerevisiae. Teste MA, et al. BMC Mol Biol, 2009 Oct 30. PMID 19874630, Free PMC Article

See all (128) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
contributes_to RNA polymerase II general transcription initiation factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables chromatin binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables molecular adaptor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables promoter-specific chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in DNA-templated transcription initiation IEA
Inferred from Electronic Annotation
more info
  
involved_in RNA polymerase II preinitiation complex assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in chromatin organization IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transcription initiation at RNA polymerase II promoter IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of SAGA complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of SAGA complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of SLIK (SAGA-like) complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of transcription factor TFIID complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transcription factor TFIID complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
Taf10p
NP_010451.3
  • Subunit (145 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    789449..790069
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180474.3 → NP_010451.3  TPA: Taf10p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010451.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VSE7, Q12030
    UniProtKB/TrEMBL
    A6ZYC5, B3LGB7, B5VG62, C7GQF2, G2WAR5, N1P6Q6
    Conserved Domains (1) summary
    COG5162
    Location:1 → 206
    COG5162; Transcription initiation factor TFIID, subunit TAF10 (also component of histone acetyltransferase SAGA) [Transcription]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12030.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools
Miscellaneous