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RPA14 DNA-directed RNA polymerase I subunit RPA14 [ Saccharomyces cerevisiae S288C ]

Gene ID: 851734, updated on 2-Nov-2024

Summary

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Official Symbol
RPA14
Official Full Name
DNA-directed RNA polymerase I subunit RPA14
Primary source
SGD:S000002563
Locus tag
YDR156W
See related
AllianceGenome:SGD:S000002563; FungiDB:YDR156W; VEuPathDB:YDR156W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Contributes to RNA polymerase I activity. Involved in nucleolar large rRNA transcription by RNA polymerase I. Part of RNA polymerase I complex. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See RPA14 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (769525..769938)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Ent5p Neighboring gene peptidylprolyl isomerase CPR1 Neighboring gene uncharacterized protein Neighboring gene aspartate-semialdehyde dehydrogenase Neighboring gene Sac3p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The association of three subunits with yeast RNA polymerase is stabilized by A14. Smid A, et al. J Biol Chem, 1995 Jun 2. PMID 7768955
  2. Crystallization of RNA polymerase I subcomplex A14/A43 by iterative prediction, probing and removal of flexible regions. Geiger SR, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2008 May 1. PMID 18453714, Free PMC Article
  3. Structural and functional homology between the RNAP(I) subunits A14/A43 and the archaeal RNAP subunits E/F. Meka H, et al. Nucleic Acids Res, 2003 Aug 1. PMID 12888498, Free PMC Article
  4. Generation of Fluorescent Versions of Saccharomyces cerevisiae RPA to Study the Conformational Dynamics of Its ssDNA-Binding Domains. Kuppa S, et al. Methods Mol Biol, 2021. PMID 33847957, Free PMC Article
  5. The A14-A43 heterodimer subunit in yeast RNA pol I and their relationship to Rpb4-Rpb7 pol II subunits. Peyroche G, et al. Proc Natl Acad Sci U S A, 2002 Nov 12. PMID 12407181, Free PMC Article

See all (88) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
contributes_to RNA polymerase I activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in nucleolar large rRNA transcription by RNA polymerase I IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in nucleolar large rRNA transcription by RNA polymerase I IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of cell size HMP PubMed 
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in transcription by RNA polymerase I IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of DNA-directed RNA polymerase complex IEA
Inferred from Electronic Annotation
more info
  
part_of RNA polymerase I complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DNA-directed RNA polymerase I subunit RPA14
NP_010440.1
  • RNA polymerase I subunit A14

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    769525..769938
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180463.1 → NP_010440.1  TPA: DNA-directed RNA polymerase I subunit RPA14 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010440.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VSD7, P50106
    UniProtKB/TrEMBL
    A6ZYB5, B3LGC7, C7GX37, C8Z571, G2WAQ5, N1PAE4
    Conserved Domains (1) summary
    pfam08203
    Location:18 → 102
    RNA_polI_A14; Yeast RNA polymerase I subunit RPA14
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P50106.1

Gene LinkOut

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