U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

BUG1 Bug1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851459, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
BUG1
Official Full Name
Bug1p
Primary source
SGD:S000002257
Locus tag
YDL099W
See related
AllianceGenome:SGD:S000002257; FungiDB:YDL099W; VEuPathDB:YDL099W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in endoplasmic reticulum to Golgi vesicle-mediated transport and protein secretion. Located in cis-Golgi network. [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See BUG1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (283419..284444)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene serine/threonine protein kinase DUN1 Neighboring gene guanine nucleotide exchange factor GET3 Neighboring gene U4/U6-U5 snRNP complex subunit SNU23 Neighboring gene proteasome regulatory particle lid subunit RPN6

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Biogenesis of a novel compartment for autophagosome-mediated unconventional protein secretion. Bruns C, et al. J Cell Biol, 2011 Dec 12. PMID 22144692, Free PMC Article
  2. The yeast orthologue of GRASP65 forms a complex with a coiled-coil protein that contributes to ER to Golgi traffic. Behnia R, et al. J Cell Biol, 2007 Jan 29. PMID 17261844, Free PMC Article
  3. Unconventional secretion of Acb1 is mediated by autophagosomes. Duran JM, et al. J Cell Biol, 2010 Feb 22. PMID 20156967, Free PMC Article
  4. Profiling lipid-protein interactions using nonquenched fluorescent liposomal nanovesicles and proteome microarrays. Lu KY, et al. Mol Cell Proteomics, 2012 Nov. PMID 22843995, Free PMC Article
  5. Prion formation and polyglutamine aggregation are controlled by two classes of genes. Manogaran AL, et al. PLoS Genet, 2011 May. PMID 21625618, Free PMC Article

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IPI
Inferred from Physical Interaction
more info
 PubMed 
involved_in protein secretion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in cis-Golgi network IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cis-Golgi network IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in cytoplasm HDA PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
Bug1p
NP_010184.1
  • Cis-golgi localized protein involved in ER to Golgi transport; forms a complex with the mammalian GRASP65 homolog, Grh1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    283419..284444
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180158.1 → NP_010184.1  TPA: Bug1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010184.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRQ1, Q12191
    Conserved Domains (1) summary
    COG3883
    Location:191 → 272
    CwlO1; Uncharacterized N-terminal domain of peptidoglycan hydrolase CwlO [Function unknown]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12191.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools