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NRP1 Nrp1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851387, updated on 2-Nov-2024

Summary

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Official Symbol
NRP1
Official Full Name
Nrp1p
Primary source
SGD:S000002326
Locus tag
YDL167C
See related
AllianceGenome:SGD:S000002326; FungiDB:YDL167C; VEuPathDB:YDL167C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable mRNA binding activity. Located in cytoplasmic stress granule. Orthologous to several human genes including TEX13C (TEX13 family member C); TEX13D (TEX13 family member D); and TEX13A (testis expressed 13A). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See NRP1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (160995..163154, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Ugx2p Neighboring gene bifunctional alcohol dehydrogenase/S-(hydroxymethyl)glutathione dehydrogenase Neighboring gene nucleoside-triphosphatase Neighboring gene CCR4-NOT core subunit CDC36

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Disruption and functional analysis of six ORFs of chromosome IV: YDL103c (QRI1), YDL105w (QRI2), YDL112w (TRM3), YDL113c, YDL116w (NUP84) and YDL167c (NRP1). Reynaud A, et al. Yeast, 2001 Feb. PMID 11180460
  2. Cellular factors required for protection from hyperoxia toxicity in Saccharomyces cerevisiae. Outten CE, et al. Biochem J, 2005 May 15. PMID 15641941, Free PMC Article
  3. Evolutionary adaptation after crippling cell polarization follows reproducible trajectories. Laan L, et al. Elife, 2015 Oct 1. PMID 26426479, Free PMC Article
  4. Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules. Kroschwald S, et al. Elife, 2015 Aug 4. PMID 26238190, Free PMC Article
  5. Molecular chaperones and stress-inducible protein-sorting factors coordinate the spatiotemporal distribution of protein aggregates. Malinovska L, et al. Mol Biol Cell, 2012 Aug. PMID 22718905, Free PMC Article

See all (52) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm HDA PubMed 
located_in cytoplasmic stress granule HDA PubMed 
located_in cytoplasmic stress granule IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Nrp1p
NP_010114.1
  • Putative RNA binding hypothetical protein; localizes to stress granules induced by glucose deprivation; predicted to be involved in ribosome biogenesis

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    160995..163154 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180227.1 → NP_010114.1  TPA: Nrp1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010114.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRI4, P32770, Q12228
    UniProtKB/TrEMBL
    B5VFA5, C7GL15, C8Z6D6
    Conserved Domains (3) summary
    sd00029
    Location:585 → 604
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    pfam00641
    Location:581 → 609
    zf-RanBP; Zn-finger in Ran binding protein and others
    cd12452
    Location:226 → 328
    RRM_ARP_like; RNA recognition motif (RRM) found in yeast asparagine-rich protein (ARP) and similar proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P32770.2

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