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MFG1 Mfg1p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851365, updated on 2-Nov-2024

Summary

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Official Symbol
MFG1
Official Full Name
Mfg1p
Primary source
SGD:S000002392
Locus tag
YDL233W
See related
AllianceGenome:SGD:S000002392; FungiDB:YDL233W; VEuPathDB:YDL233W
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See MFG1 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (36797..38173)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Ypd1p Neighboring gene GTPase-activating protein GYP7 Neighboring gene olichyl-diphosphooligosaccharide--protein glycotransferase OST4 Neighboring gene Bre4p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identifying molecular features that are associated with biological function of intrinsically disordered protein regions. Zarin T, et al. Elife, 2021 Feb 22. PMID 33616531, Free PMC Article
  2. Composition-based prediction and rational manipulation of prion-like domain recruitment to stress granules. Boncella AE, et al. Proc Natl Acad Sci U S A, 2020 Mar 17. PMID 32127480, Free PMC Article
  3. The Absence of the Transcription Factor Yrr1p, Identified from Comparative Genome Profiling, Increased Vanillin Tolerance Due to Enhancements of ABC Transporters Expressing, rRNA Processing and Ribosome Biogenesis in Saccharomyces cerevisiae. Wang X, et al. Front Microbiol, 2017. PMID 28360888, Free PMC Article
  4. Global gene deletion analysis exploring yeast filamentous growth. Ryan O, et al. Science, 2012 Sep 14. PMID 22984072
  5. Transcription factor regulation and chromosome dynamics during pseudohyphal growth. Mayhew D, et al. Mol Biol Cell, 2014 Sep 1. PMID 25009286, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm HDA PubMed 
located_in nucleus HDA PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of transcription regulator complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Mfg1p
NP_010048.1
  • Regulator of filamentous growth; interacts with FLO11 promoter and regulates FLO11 expression; binds to transcription factors Flo8p and Mss11p; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YDL233W is not an essential gene

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    36797..38173
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180293.1 → NP_010048.1  TPA: Mfg1p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010048.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRC3, Q07684
    UniProtKB/TrEMBL
    A6ZXA1, B3LHA9, C7GJQ2, N1P5M5
    Conserved Domains (2) summary
    pfam01803
    Location:151 → 393
    LIM_bind; LIM-domain binding protein
    pfam03154
    Location:24 → 137
    Atrophin-1; Atrophin-1 family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q07684.1

Gene LinkOut

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