SEC31 Sec31p [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: SEC31
Official Full Name: Sec31p
Primary source: SGD:S000002354
Locus tag: YDL195W
See related: AllianceGenome:SGD:S000002354; FungiDB:YDL195W; VEuPathDB:YDL195W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as: WEB1
Summary: Enables structural molecule activity. Involved in COPII-coated vesicle budding. Located in mating projection tip. Part of COPII vesicle coat. Human ortholog(s) of this gene implicated in Halperin-Birk syndrome. Orthologous to several human genes including SEC31A (SEC31 homolog A, COPII coat complex component). [provided by Alliance of Genome Resources, Nov 2024]
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Chromosome IV - NC_001136.10 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables structural molecule activity	IBA Inferred from Biological aspect of Ancestor more info
enables structural molecule activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in COPII-coated vesicle budding	IDA Inferred from Direct Assay more info	PubMed
involved_in COPII-coated vesicle budding	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in COPII-coated vesicle cargo loading	IBA Inferred from Biological aspect of Ancestor more info
involved_in endoplasmic reticulum organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	IEA Inferred from Electronic Annotation more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of COPII vesicle coat	IBA Inferred from Biological aspect of Ancestor more info
part_of COPII vesicle coat	IDA Inferred from Direct Assay more info	PubMed
located_in ER to Golgi transport vesicle membrane	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum exit site	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in mating projection tip	HDA more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info

NP_010086.2

Component of the Sec13p-Sec31p complex of the COPII vesicle coat; COPII coat is required for vesicle formation in ER to Golgi transport; mutant has increased aneuploidy tolerance

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The following sections contain reference sequences that belong to a specific genome build. Explain