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FMP45 Fmp45p [ Saccharomyces cerevisiae S288C ]

Gene ID: 851304, updated on 2-Nov-2024

Summary

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Official Symbol
FMP45
Official Full Name
Fmp45p
Primary source
SGD:S000002381
Locus tag
YDL222C
See related
AllianceGenome:SGD:S000002381; FungiDB:YDL222C; VEuPathDB:YDL222C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Involved in ascospore formation and fungal-type cell wall organization. Located in cell cortex. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See FMP45 in Genome Data Viewer
Location:
chromosome: IV
Exon count:
1
Sequence:
Chromosome: IV; NC_001136.10 (60872..61801, complement)

Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Whi4p Neighboring gene Hbt1p Neighboring gene telomere-binding protein CDC13 Neighboring gene D-tyrosyl-tRNA(Tyr) deacylase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001136.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Sur7p family defines novel cortical domains in Saccharomyces cerevisiae, affects sphingolipid metabolism, and is involved in sporulation. Young ME, et al. Mol Cell Biol, 2002 Feb. PMID 11784867, Free PMC Article
  2. The Sur7 protein regulates plasma membrane organization and prevents intracellular cell wall growth in Candida albicans. Alvarez FJ, et al. Mol Biol Cell, 2008 Dec. PMID 18799621, Free PMC Article
  3. Cloning of the multicopy suppressor gene SUR7: evidence for a functional relationship between the yeast actin-binding protein Rvs167 and a putative membranous protein. Sivadon P, et al. Yeast, 1997 Jun 30. PMID 9219339
  4. Eisosomes mark static sites of endocytosis. Walther TC, et al. Nature, 2006 Feb 23. PMID 16496001
  5. Inactivation of Ymr1, Sjl2/3 phosphatases promotes stress resistance and longevity in wild type and Ras2G19V yeast. Mirisola MG, et al. Biomed J, 2024 Apr. PMID 38154617, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in ascospore formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cortical actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fungal-type cell wall organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in fungal-type cell wall organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in septin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sporulation resulting in formation of a cellular spore IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cell cortex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cell cortex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cell periphery HDA PubMed 
is_active_in membrane raft IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion HDA PubMed 
located_in plasma membrane HDA PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Fmp45p
NP_010059.1
  • Integral membrane protein localized to mitochondria; required for sporulation and maintaining sphingolipid content; similar to SUR7; FMP45 has a paralog, YNL194C, that arose from the whole genome duplication

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001136.10 Reference assembly

    Range
    60872..61801 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001180282.1 → NP_010059.1  TPA: Fmp45p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_010059.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VRD3, Q07651
    UniProtKB/TrEMBL
    B3LHA1, B5VF55, C7GSV6, C8Z6P7, N1P5Z4
    Conserved Domains (1) summary
    pfam06687
    Location:22 → 205
    SUR7; SUR7/PalI family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q07651.1

Gene LinkOut

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