ATP14 F1F0 ATP synthase subunit h [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: ATP14
Official Full Name: F1F0 ATP synthase subunit h
Primary source: SGD:S000004286
Locus tag: YLR295C
See related: AllianceGenome:SGD:S000004286; FungiDB:YLR295C; VEuPathDB:YLR295C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Contributes to ATP hydrolysis activity and proton-transporting ATP synthase activity, rotational mechanism. Involved in cristae formation; mitochondrial proton-transporting ATP synthase complex assembly; and proton motive force-driven ATP synthesis. Located in mitochondrion. Part of proton-transporting ATP synthase complex, coupling factor F(o). [provided by Alliance of Genome Resources, Nov 2024]
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Chromosome XII - NC_001144.5 Genomic Context describing neighboring genes

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Yeast cells depleted in Atp14p fail to assemble Atp6p within the ATP synthase and exhibit altered mitochondrial cristae morphology
Title: Yeast cells depleted in Atp14p fail to assemble Atp6p within the ATP synthase and exhibit altered mitochondrial cristae morphology.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to ATP hydrolysis activity	IDA Inferred from Direct Assay more info	PubMed
contributes_to proton-transporting ATP synthase activity, rotational mechanism	IBA Inferred from Biological aspect of Ancestor more info
contributes_to proton-transporting ATP synthase activity, rotational mechanism	IDA Inferred from Direct Assay more info	PubMed
contributes_to proton-transporting ATP synthase activity, rotational mechanism	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in ATP biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in cristae formation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitochondrial proton-transporting ATP synthase complex assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in proton motive force-driven ATP synthesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in proton motive force-driven ATP synthesis	IDA Inferred from Direct Assay more info	PubMed
involved_in proton motive force-driven ATP synthesis	IEA Inferred from Electronic Annotation more info
involved_in proton motive force-driven ATP synthesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in proton transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
part_of proton-transporting ATP synthase complex, coupling factor F(o)	IEA Inferred from Electronic Annotation more info
part_of proton-transporting ATP synthase complex, coupling factor F(o)	IMP Inferred from Mutant Phenotype more info	PubMed

NP_013398.1

Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase; F1F0 ATP synthase is a large, evolutionarily conserved enzyme complex required for ATP synthesis; protein abundance increases in response to DNA replication stress