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ADY4 Ady4p [ Saccharomyces cerevisiae S288C ]

Gene ID: 850924, updated on 2-Nov-2024

Summary

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Official Symbol
ADY4
Official Full Name
Ady4p
Primary source
SGD:S000004217
Locus tag
YLR227C
See related
AllianceGenome:SGD:S000004217; FungiDB:YLR227C; VEuPathDB:YLR227C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables structural molecule activity. Involved in ascospore formation. Located in meiotic spindle pole body. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ADY4 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (590562..592043, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Bur2p Neighboring gene tRNA-Leu Neighboring gene gag protein Neighboring gene gag-pol fusion protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001144.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Recruitment of the lipid kinase Mss4 to the meiotic spindle pole promotes prospore membrane formation in Saccharomyces cerevisiae. Nunez G, et al. Mol Biol Cell, 2023 Apr 1. PMID 36857169, Free PMC Article
  2. Membrane assembly modulates the stability of the meiotic spindle-pole body. Mathieson EM, et al. J Cell Sci, 2010 Jul 15. PMID 20592185, Free PMC Article
  3. Ady4p and Spo74p are components of the meiotic spindle pole body that promote growth of the prospore membrane in Saccharomyces cerevisiae. Nickas ME, et al. Eukaryot Cell, 2003 Jun. PMID 12796288, Free PMC Article
  4. A screen for genes required for meiosis and spore formation based on whole-genome expression. Rabitsch KP, et al. Curr Biol, 2001 Jul 10. PMID 11470404
  5. An overexpression screen in Saccharomyces cerevisiae identifies novel genes that affect endocytic protein trafficking. Arlt H, et al. Traffic, 2011 Nov. PMID 21777356

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables structural molecule activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural molecule activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in ascospore formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in sporulation resulting in formation of a cellular spore IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in meiotic spindle pole body IDA
Inferred from Direct Assay
more info
 PubMed 
located_in meiotic spindle pole body IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in spindle pole body IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Ady4p
NP_013328.1
  • Structural component of the meiotic outer plaque; outer plaque is a membrane-organizing center that assembles on the cytoplasmic face of the spindle pole body during meiosis II and triggers the formation of the prospore membrane

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    590562..592043 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001182114.1 → NP_013328.1  TPA: Ady4p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013328.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VYM7, Q05955
    UniProtKB/TrEMBL
    C8ZDJ1, N1P6W5
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q05955.1

Gene LinkOut

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