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ARP6 Arp6p [ Saccharomyces cerevisiae S288C ]

Gene ID: 850774, updated on 18-Sep-2024

Summary

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Official Symbol
ARP6
Official Full Name
Arp6p
Primary source
SGD:S000004075
Locus tag
YLR085C
See related
AllianceGenome:SGD:S000004075; FungiDB:YLR085C; VEuPathDB:YLR085C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Enables nucleosome binding activity. Involved in histone exchange. Located in cytoplasm and nuclear periphery. Part of Swr1 complex. Orthologous to human ACTR6 (actin related protein 6). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See ARP6 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (300673..301989, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Emp70p Neighboring gene Rax2p Neighboring gene condensin subunit SMC4 Neighboring gene Csf1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001144.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Yeast Actin-Related Protein ARP6 Negatively Regulates Agrobacterium-Mediated Transformation of Yeast Cell. Luo Y, et al. Biomed Res Int, 2015. PMID 26425545, Free PMC Article
  2. Actin-related protein Arp6 influences H2A.Z-dependent and -independent gene expression and links ribosomal protein genes to nuclear pores. Yoshida T, et al. PLoS Genet, 2010 Apr 15. PMID 20419146, Free PMC Article
  3. The INO80 complex is required for damage-induced recombination. Kawashima S, et al. Biochem Biophys Res Commun, 2007 Apr 13. PMID 17320816
  4. The nuclear actin-related protein ARP6 is a pleiotropic developmental regulator required for the maintenance of FLOWERING LOCUS C expression and repression of flowering in Arabidopsis. Deal RB, et al. Plant Cell, 2005 Oct. PMID 16141450, Free PMC Article
  5. Multiple actin-related proteins of Saccharomyces cerevisiae are present in the nucleus. Harata M, et al. J Biochem, 2000 Oct. PMID 11011149

See all (98) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables nucleosome binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleosome binding IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
  
involved_in chromatin remodeling IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in chromatin remodeling IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of Swr1 complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Swr1 complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in intracellular non-membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
  
located_in nuclear periphery IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Arp6p
NP_013186.1
  • Actin-related protein that binds nucleosomes; a component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    300673..301989 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181972.1 → NP_013186.1  TPA: Arp6p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013186.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VY85, Q12509
    UniProtKB/TrEMBL
    A7A0Y9, B3LT53, C7GQQ9, C8ZD56, G2WIS7, N1NZJ6
    Conserved Domains (1) summary
    smart00268
    Location:3 → 433
    ACTIN; Actin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q12509.1

Gene LinkOut

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