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THI73 Thi73p [ Saccharomyces cerevisiae S288C ]

Gene ID: 850690, updated on 18-Sep-2024

Summary

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Official Symbol
THI73
Official Full Name
Thi73p
Primary source
SGD:S000003994
Locus tag
YLR004C
See related
AllianceGenome:SGD:S000003994; FungiDB:YLR004C; VEuPathDB:YLR004C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in endoplasmic reticulum. Orthologous to human SLC37A2 (solute carrier family 37 member 2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See THI73 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (157934..159505, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Noc3p Neighboring gene Cms1p Neighboring gene TFIIH/NER complex subunit SSL1 Neighboring gene mitogen-activated protein kinase kinase kinase SSK1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001144.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unified inventory of established and putative transporters encoded within the complete genome of Saccharomyces cerevisiae. Paulsen IT, et al. FEBS Lett, 1998 Jun 23. PMID 9678606
  2. Transcriptional regulation of the Saccharomyces cerevisiae DAL5 gene family and identification of the high affinity nicotinic acid permease TNA1 (YGR260w). Llorente B, et al. FEBS Lett, 2000 Jun 23. PMID 10869563
  3. Ammonia pulses and metabolic oscillations guide yeast colony development. Palková Z, et al. Mol Biol Cell, 2002 Nov. PMID 12429834, Free PMC Article
  4. Genome-wide responses to mitochondrial dysfunction. Epstein CB, et al. Mol Biol Cell, 2001 Feb. PMID 11179416, Free PMC Article
  5. Pdc2 coordinates expression of the THI regulon in the yeast Saccharomyces cerevisiae. Mojzita D, et al. Mol Genet Genomics, 2006 Aug. PMID 16850348

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in cell periphery HDA PubMed 
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Thi73p
NP_013104.1
  • Putative plasma membrane permease; proposed to be involved in carboxylic acid uptake and repressed by thiamine; substrate of Dbf2p/Mob1p kinase; transcription is altered if mitochondrial dysfunction occurs

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    157934..159505 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181891.1 → NP_013104.1  TPA: Thi73p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013104.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VY06, Q07904
    UniProtKB/TrEMBL
    A7A0Q9, B3LTG9, C7GPF4, C8ZCX6, G2WIJ8, N1NYZ1
    Conserved Domains (1) summary
    cd17327
    Location:77 → 481
    MFS_FEN2_like; Pantothenate transporter FEN2 and similar transporters of the Major Facilitator Superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q07904.1

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