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GPI13 mannose-ethanolamine phosphotransferase GPI13 [ Saccharomyces cerevisiae S288C ]

Gene ID: 850628, updated on 18-Sep-2024

Summary

Official Symbol
GPI13
Official Full Name
mannose-ethanolamine phosphotransferase GPI13
Primary source
SGD:S000003954
Locus tag
YLL031C
See related
AllianceGenome:SGD:S000003954; FungiDB:YLL031C; VEuPathDB:YLL031C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
MPC1
Summary
Enables mannose-ethanolamine phosphotransferase activity. Involved in GPI anchor biosynthetic process. Located in endoplasmic reticulum. Orthologous to human PIGO (phosphatidylinositol glycan anchor biosynthesis class O). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

See GPI13 in Genome Data Viewer
Location:
chromosome: XII
Exon count:
1
Sequence:
Chromosome: XII; NC_001144.5 (77152..80205, complement)

Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Irc19p Neighboring gene uncharacterized protein Neighboring gene Rrt7p Neighboring gene aminopeptidase P

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables mannose-ethanolamine phosphotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables mannose-ethanolamine phosphotransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables mannose-ethanolamine phosphotransferase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity, transferring phosphorus-containing groups IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables zinc ion binding RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in GPI anchor biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in GPI anchor biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in cell wall organization IEA
Inferred from Electronic Annotation
more info
 
involved_in organophosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in phosphate-containing compound metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum HDA PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
mannose-ethanolamine phosphotransferase GPI13
NP_013069.1
  • ER membrane localized phosphoryltransferase; adds phosphoethanolamine onto the third mannose residue of the glycosylphosphatidylinositol (GPI) anchor precursor; similar to human PIG-O protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001144.5 Reference assembly

    Range
    77152..80205 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001181851.1NP_013069.1  TPA: mannose-ethanolamine phosphotransferase GPI13 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_013069.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VXX4, Q07830
    UniProtKB/TrEMBL
    C7GQE2, C8ZCU2, G2WIG5, N1NZH3
    Conserved Domains (2) summary
    COG1524
    Location:48701
    Npp1; Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily [General function prediction only]
    cd16023
    Location:77367
    GPI_EPT_3; GPI ethanolamine phosphate transferase 3, PIG-O