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AIP5 Aip5p [ Saccharomyces cerevisiae S288C ]

Gene ID: 850570, updated on 18-Sep-2024

Summary

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Official Symbol
AIP5
Official Full Name
Aip5p
Primary source
SGD:S000001912
Locus tag
YFR016C
See related
AllianceGenome:SGD:S000001912; FungiDB:YFR016C; VEuPathDB:YFR016C
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Acts upstream of or within positive regulation of actin filament bundle assembly. Located in cellular bud neck and cellular bud tip. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See AIP5 in Genome Data Viewer
Location:
chromosome: VI
Exon count:
1
Sequence:
Chromosome: VI; NC_001138.5 (177042..180743, complement)

Chromosome VI - NC_001138.5Genomic Context describing neighboring genes Neighboring gene calmodulin-dependent protein kinase CMK1 Neighboring gene glycogen (starch) synthase GSY1 Neighboring gene tRNA-Gly Neighboring gene Igd1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001138.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Polarisome scaffolder Spa2-mediated macromolecular condensation of Aip5 for actin polymerization. Xie Y, et al. Nat Commun, 2019 Nov 7. PMID 31699995, Free PMC Article
  2. A teamwork promotion of formin-mediated actin nucleation by Bud6 and Aip5 in Saccharomyces cerevisiae. Xie Y, et al. Mol Biol Cell, 2022 Feb 1. PMID 34818061, Free PMC Article
  3. Cell polarity protein Spa2P associates with proteins involved in actin function in Saccharomyces cerevisiae. Shih JL, et al. Mol Biol Cell, 2005 Oct. PMID 16030260, Free PMC Article
  4. Yeast Nap1-binding protein Nbp2p is required for mitotic growth at high temperatures and for cell wall integrity. Ohkuni K, et al. Genetics, 2003 Oct. PMID 14573466, Free PMC Article
  5. The cell polarity proteins Boi1 and Boi2 direct an actin nucleation complex to sites of exocytosis in Saccharomyces cerevisiae. Glomb O, et al. J Cell Sci, 2020 Feb 13. PMID 31964708

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of actin filament bundle assembly IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cellular bud HDA PubMed 
located_in cellular bud neck IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cellular bud tip IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm HDA PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
Aip5p
NP_116671.1
  • Protein that positively regulates actin assembly; forms a homodimer and interacts with G-actin; localization to the bud neck and bud tip requires Spa2p; YFR016C is not an essential gene

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001138.5 Reference assembly

    Range
    177042..180743 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001179981.1 → NP_116671.1  TPA: Aip5p [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_116671.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6VTP7, P43597
    UniProtKB/TrEMBL
    G2WDF5
    Conserved Domains (2) summary
    PTZ00121
    Location:482 → 1082
    PTZ00121; MAEBL; Provisional
    TIGR00927
    Location:271 → 528
    2A1904; K+-dependent Na+/Ca+ exchanger
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P43597.1

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