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SUP61 [ Saccharomyces cerevisiae S288C ]

Gene ID: 850426, updated on 2-Nov-2024

Summary

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Official Symbol
SUP61
Primary source
SGD:S000006730
Locus tag
YNCC0013W
See related
AllianceGenome:SGD:S000006730
Gene type
tRNA
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary
Predicted to enable triplet codon-amino acid adaptor activity. Predicted to be involved in translational elongation. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See SUP61 in Genome Data Viewer
Location:
chromosome: III
Sequence:
Chromosome: III; NC_001135.5 (227942..228042)

Chromosome III - NC_001135.5Genomic Context describing neighboring genes Neighboring gene Tah1p Neighboring gene Tvs1p Neighboring gene U2 snRNP complex subunit BUD31 Neighboring gene Hcm1p

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001135.5

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Recessive lethal amber suppressors in yeast. Brandriss MC, et al. Genetics, 1975 Apr. PMID 1093932, Free PMC Article
  2. Testing for intron function in the essential Saccharomyces cerevisiae tRNA(SerUCG) gene. Ho CK, et al. J Mol Biol, 1988 Aug 5. PMID 3050130
  3. Recessive lethality of yeast strains carrying the SUP61 suppressor results from loss of a transfer RNA with a unique decoding function. Etcheverry T, et al. J Mol Biol, 1982 Jul 15. PMID 6750138
  4. Only one of two closely related yeast suppressor tRNA genes contains an intervening sequence. Olson MV, et al. Nature, 1981 Jun 11. PMID 6262655
  5. The yeast rapid tRNA decay pathway primarily monitors the structural integrity of the acceptor and T-stems of mature tRNA. Whipple JM, et al. Genes Dev, 2011 Jun 1. PMID 21632824, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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  • Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE analysis; i6A37 modification is catalyzed by Mod5p; can mutate to suppress amber or ochre nonsense mutations; suppressor mutant alleles are recessive lethal and can only be maintained when an additional wild-type copy of the gene is present, because SUP61 encodes the only tRNA species that can decode UCG codons

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables triplet codon-amino acid adaptor activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in translational elongation IC
Inferred by Curator
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IC
Inferred by Curator
more info
 PubMed 

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