ddf2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ddf2
Primary source: Araport:AT1G63030
Locus tag: AT1G63030
See related: TAIR:AT1G63030
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: DWARF AND DELAYED FLOWERING 2; F16P17.20; F16P17_20
Summary: encodes a member of the DREB subfamily A-1 of ERF/AP2 transcription factor family (DDF2). The protein contains one AP2 domain. There are six members in this subfamily, including CBF1, CBF2, and CBF3. Overexpression of this gene results in the reduction of gibberellic acid biosynthesis. This gene is expressed in all tissues examined, but most abundantly expressed in rosette leaves and stems. Overexpression of DDF1, a putative paralog of this gene, also reduces gibberellic acid biosynthesis and makes the plants more tolerant to high-salinity levels.
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Genomic context

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Location:: chromosome: 1

Exon count:: 1

Sequence:: Chromosome: 1; NC_003070.9 (23367394..23368416, complement)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data indicate that both transcription factors DWARF AND DELAYED FLOWERING1 (DDF1) and DDF2 are under selective constraint.
Title: Molecular Evidence for Functional Divergence and Decay of a Transcription Factor Derived from Whole-Genome Duplication in Arabidopsis thaliana.
Data indicate that the transcript levels of HAK5 and four transcriptin factor genes DDF2, JLO, bHLH121 and TFII_A were highly up-regulated in response to both -K and salt stress.
Title: Identification and characterization of transcription factors regulating Arabidopsis HAK5.

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General gene information

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Homology

Orthologs from OrthoDB

NM_001084295.2

Supported by ESTs:

NM_104981.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of gibberellin biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of timing of transition from vegetative to reproductive phase	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: Integrase-type DNA-binding superfamily protein

NP_001077764.1

DWARF AND DELAYED FLOWERING 2 (ddf2); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: Integrase-type DNA-binding superfamily protein (TAIR:AT1G12610.1); Has 5240 Blast hits to 5238 proteins in 236 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 5235; Viruses - 0; Other Eukaryotes - 5 (source: NCBI BLink).

NP_176491.1

DWARF AND DELAYED FLOWERING 2 (ddf2); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: Integrase-type DNA-binding superfamily protein (TAIR:AT1G12610.1); Has 5240 Blast hits to 5238 proteins in 236 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 5235; Viruses - 0; Other Eukaryotes - 5 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

23367394..23368416 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001084295.2 → NP_001077764.1 Integrase-type DNA-binding superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001077764.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q1ECJ2, Q680B6, Q6J9T4, Q9SGJ6

UniProtKB/TrEMBL

A0A5S9WT19, A0A654EKI6

Conserved Domains (1) summary

cd00018
Location:28 → 88

AP2; DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor ...
NM_104981.4 → NP_176491.1 Integrase-type DNA-binding superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_176491.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q1ECJ2, Q680B6, Q6J9T4, Q9SGJ6

UniProtKB/TrEMBL

A0A5S9WT19, A0A654EKI6

Conserved Domains (1) summary

cd00018
Location:28 → 88

AP2; DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor ...