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AAE18 acyl-activating enzyme 18 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 841977, updated on 18-Sep-2024

Summary

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Official Symbol
AAE18
Official Full Name
acyl-activating enzyme 18
Primary source
TAIR:AT1G55320
Locus tag
AT1G55320
See related
Araport:AT1G55320
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
acyl-activating enzyme 18; F7A10.14; F7A10_14
Summary
Encodes a protein with similarity to acyl activating enzymes. AAE18 is localized to the peroxisome where it may be involved in metabolism of auxin precursors to active auxins.
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Genomic context

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See AAE18 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
14
Sequence:
Chromosome: 1; NC_003070.9 (20633096..20636892)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene TBP-associated factor 7 Neighboring gene SC35-like splicing factor 33 Neighboring gene RNA polymerase II transcription mediator Neighboring gene uncharacterized protein Neighboring gene arabinogalactan protein 21

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of two Arabidopsis genes encoding a peroxisomal oxidoreductase-like protein and an acyl-CoA synthetase-like protein that are required for responses to pro-auxins. Wiszniewski AA, et al. Plant Mol Biol, 2009 Mar. PMID 19043666
  2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. An updated model for peroxisomal pro-auxin metabolism in Arabidopsis that includes SDRa and AAE18 is presented. AAE18 is capable of activating 2,4-dichlorophenoxybutyric acid (2,4-DB). [AAE18]
    Title: Identification of two Arabidopsis genes encoding a peroxisomal oxidoreductase-like protein and an acyl-CoA synthetase-like protein that are required for responses to pro-auxins.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

NM_001084254.1
NM_104408.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within auxin metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in peroxisome IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
acyl-activating enzyme 18
NP_001077723.1
  • acyl-activating enzyme 18 (AAE18); FUNCTIONS IN: catalytic activity, ligase activity; INVOLVED IN: metabolic process, auxin metabolic process; LOCATED IN: peroxisome; EXPRESSED IN: guard cell; CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: acyl-activating enzyme 17 (TAIR:AT5G23050.1); Has 26488 Blast hits to 26111 proteins in 2320 species: Archae - 743; Bacteria - 16022; Metazoa - 855; Fungi - 842; Plants - 335; Viruses - 0; Other Eukaryotes - 7691 (source: NCBI BLink).
NP_175929.3
  • acyl-activating enzyme 18 (AAE18); FUNCTIONS IN: catalytic activity, ligase activity; INVOLVED IN: metabolic process, auxin metabolic process; LOCATED IN: peroxisome; EXPRESSED IN: guard cell; CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: acyl-activating enzyme 17 (TAIR:AT5G23050.1); Has 28626 Blast hits to 28179 proteins in 2353 species: Archae - 768; Bacteria - 16970; Metazoa - 908; Fungi - 873; Plants - 384; Viruses - 0; Other Eukaryotes - 8723 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    20633096..20636892
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_104408.5 → NP_175929.3  acyl-activating enzyme 18 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_175929.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    F4I094, Q84P17, Q8GZ95, Q9C8A3
    UniProtKB/TrEMBL
    A0A178WMT3, A0A5S9WPV1
    Conserved Domains (1) summary
    PLN03052
    Location:1 → 727
    PLN03052; acetate--CoA ligase; Provisional

  2. NM_001084254.1 → NP_001077723.1  acyl-activating enzyme 18 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001077723.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q84P17
    Conserved Domains (2) summary
    PLN03051
    Location:21 → 511
    PLN03051; acyl-activating enzyme; Provisional
    cl17068
    Location:12 → 498
    AFD_class_I; Adenylate forming domain, Class I superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q84P17.1

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