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PDH-E1 BETA pyruvate dehydrogenase E1 beta [ Arabidopsis thaliana (thale cress) ]

Gene ID: 839891, updated on 18-Sep-2024

Summary

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Official Symbol
PDH-E1 BETA
Official Full Name
pyruvate dehydrogenase E1 beta
Primary source
TAIR:AT1G30120
Locus tag
AT1G30120
See related
Araport:AT1G30120
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
pyruvate dehydrogenase E1 beta
Summary
Encodes a putative plastid pyruvate dehydrogenase E1 beta subunit that is distinct from the mitochondrial pyruvate dehydrogenase E1 beta subunit.
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Genomic context

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See PDH-E1 BETA in Genome Data Viewer
Location:
chromosome: 1
Exon count:
4
Sequence:
Chromosome: 1; NC_003070.9 (10584105..10586680, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene nine-cis-epoxycarotenoid dioxygenase 5 Neighboring gene nudix hydrolase homolog 25 Neighboring gene DUF1365 family protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning and molecular analyses of the Arabidopsis thaliana plastid pyruvate dehydrogenase subunits. Johnston ML, et al. Biochim Biophys Acta, 1997 Oct 20. PMID 9393637
  2. Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana. Ferro M, et al. Mol Cell Proteomics, 2003 May. PMID 12766230
  3. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article
  4. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
  5. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_102751.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables pyruvate dehydrogenase (acetyl-transferring) activity TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA biosynthetic process from pyruvate IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within fatty acid biosynthetic process TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast TAS
Traceable Author Statement
more info
 PubMed 
located_in chloroplast envelope HDA PubMed 
located_in chloroplast stroma HDA PubMed 
located_in nucleus HDA PubMed 
part_of pyruvate dehydrogenase complex TAS
Traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
pyruvate dehydrogenase E1 beta
NP_174304.1
  • pyruvate dehydrogenase E1 beta (PDH-E1 BETA); FUNCTIONS IN: pyruvate dehydrogenase (acetyl-transferring) activity; INVOLVED IN: fatty acid biosynthetic process; LOCATED IN: plastid pyruvate dehydrogenase complex, chloroplast, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Transketolase, C-terminal (InterPro:IPR005476), Transketolase-like, C-terminal (InterPro:IPR015941), Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II (InterPro:IPR009014), Transketolase-like, pyrimidine-binding domain (InterPro:IPR005475); BEST Arabidopsis thaliana protein match is: Transketolase family protein (TAIR:AT2G34590.1); Has 14229 Blast hits to 14219 proteins in 2378 species: Archae - 200; Bacteria - 8952; Metazoa - 481; Fungi - 222; Plants - 270; Viruses - 0; Other Eukaryotes - 4104 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    10584105..10586680 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_102751.5 → NP_174304.1  pyruvate dehydrogenase E1 beta [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_174304.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O24458, Q9C6Z3
    UniProtKB/TrEMBL
    A0A178WIN0, A0A5S9WD50
    Conserved Domains (3) summary
    cd07036
    Location:90 → 256
    TPP_PYR_E1-PDHc-beta_like; Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins
    CHL00144
    Location:84 → 406
    odpB; pyruvate dehydrogenase E1 component beta subunit; Validated
    pfam02780
    Location:276 → 397
    Transketolase_C; Transketolase, C-terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9C6Z3.1

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