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MP Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 838573, updated on 18-Sep-2024

Summary

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Official Symbol
MP
Official Full Name
Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein
Primary source
TAIR:AT1G19850
Locus tag
AT1G19850
See related
Araport:AT1G19850
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARF5; AUXIN RESPONSE FACTOR 5; F6F9.10; F6F9_10; IAA24; indole-3-acetic acid inducible 24; MONOPTEROS; TRANSCRIPTION FACTOR IAA24
Summary
Encodes a transcription factor (IAA24) mediating embryo axis formation and vascular development. Similar to AUXIN RESPONSIVE FACTOR 1 (ARF1) shown to bind to auxin responsive elements (AREs), and to the maize transcriptional activator VIVIPAROUS 1(VP1). In situ hybridization shows expression in provascular tissue of embryos, the emerging shoot primordia, then is restricted to provascular tissue, and in the root central vascular cylinder.
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Genomic context

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Location:
chromosome: 1
Exon count:
13
Sequence:
Chromosome: 1; NC_003070.9 (6886669..6891404)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene filament-like protein (DUF869) Neighboring gene SAUR-like auxin-responsive protein family Neighboring gene Zinc finger C-x8-C-x5-C-x3-H type family protein Neighboring gene IQ-domain 32 Neighboring gene Regulator of chromosome condensation (RCC1) family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multiple MONOPTEROS-dependent pathways are involved in leaf initiation. Schuetz M, et al. Plant Physiol, 2008 Oct. PMID 18685044, Free PMC Article
  2. Characterization of an allelic series in the MONOPTEROS gene of Arabidopsis. Odat O, et al. Genesis, 2014 Feb. PMID 24281793
  3. Distinct subclades of Aux/IAA genes are direct targets of ARF5/MP transcriptional regulation. Krogan NT, et al. New Phytol, 2014 Nov. PMID 25145395
  4. Irrepressible MONOPTEROS/ARF5 promotes de novo shoot formation. Ckurshumova W, et al. New Phytol, 2014 Nov. PMID 25274430
  5. A dominant mutation reveals asymmetry in MP/ARF5 function along the adaxial-abaxial axis of shoot lateral organs. Krogan NT, et al. Plant Signal Behav, 2012 Aug. PMID 22751359, Free PMC Article

See all (49) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ARF4 regulates shoot regeneration through coordination with ARF5 and IAA12.
    Title: ARF4 regulates shoot regeneration through coordination with ARF5 and IAA12.
  2. Determinants of PB1 Domain Interactions in Auxin Response Factor ARF5 and Repressor IAA17.
    Title: Determinants of PB1 Domain Interactions in Auxin Response Factor ARF5 and Repressor IAA17.
  3. Auxin signaling in stem cells is mediated, at least in part, by AUXIN RESPONSE FACTOR 5/MONOPTEROS (ARF5/MP), which directly represses the transcription of DORNROSCHEN/ENHANCER OF SHOOT REGENERATION 1 (DRN/ESR1). DRN expressed in stem cells positively regulates CLAVATA3 (CLV3) expression and has important meristematic functions.
    Title: A Molecular Framework for Auxin-Controlled Homeostasis of Shoot Stem Cells in Arabidopsis.
  4. Adaxial-expressed MONOPTEROS (MP) and abaxial-enriched auxin together act as positional cues for patterning the WOX domain. MP directly binds to the WOX1 and PRS promoters and activates their expression.
    Title: Spatial Auxin Signaling Controls Leaf Flattening in Arabidopsis.
  5. MP plays a critical role in Arabidopsis embryonic root initiation.
    Title: Auxin response cell-autonomously controls ground tissue initiation in the early Arabidopsis embryo.
  6. TIR1/AFB-Aux/IAA auxin perception mediates rapid cell wall acidification and growth of Arabidopsis hypocotyls.
    Title: TIR1/AFB-Aux/IAA auxin perception mediates rapid cell wall acidification and growth of Arabidopsis hypocotyls.
  7. activating a steroid-inducible variant of the auxin response factor (ARF) MONOPTEROS (MP) is sufficient to restore patterning and PIN gene expression.
    Title: The auxin response factor MONOPTEROS controls meristem function and organogenesis in both the shoot and root through the direct regulation of PIN genes.
  8. These findings reveal a patterning module in plants that determines organ position by orienting transport of the hormone auxin toward cells with high levels of MP-mediated auxin signaling.
    Title: Auxin Acts through MONOPTEROS to Regulate Plant Cell Polarity and Pattern Phyllotaxis.
  9. In this study, it is shown that MONOPTEROS (MP) directly activates the Dof5.8 promoter. Phenotypic analysis with the mp dof5.8 double mutants revealed that mutations within Dof5.8 enhanced the phenotype of a weak allele of mp.
    Title: MONOPTEROS directly activates the auxin-inducible promoter of the Dof5.8 transcription factor gene in Arabidopsis thaliana leaf provascular cells.
  10. Analyses of the expression pattern of ARF7 and ARF5 targets suggest that this patterning mechanism controls flanking and central zone specification in Arabidopsis LR primordia.
    Title: Inference of the Arabidopsis lateral root gene regulatory network suggests a bifurcation mechanism that defines primordia flanking and central zones.
Submit: New GeneRIF Correction See all GeneRIFs (26)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Miscellaneous features

  • Loc: 6887019-6887057 AT1G19850.uORF4
  • Loc: 6887047-6887121 AT1G19850.uORF1
  • Loc: 6887080-6887121 AT1G19850.uORF3
  • Loc: 6887146-6887196 AT1G19850.uORF2
NM_001332415.1
NM_101840.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables DNA-binding transcription factor activity TAS
Traceable Author Statement
more info
 PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription cis-regulatory region binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables transcription cis-regulatory region binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within embryo development ending in seed dormancy IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within flower development IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within leaf vascular tissue pattern formation IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within longitudinal axis specification IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within meristem development IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to auxin IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within root development IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within xylem and phloem pattern formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein
NP_173414.1
  • MONOPTEROS (MP); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity, promoter binding; INVOLVED IN: in 8 processes; LOCATED IN: nucleus, membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Aux/IAA-ARF-dimerisation (InterPro:IPR011525), Transcriptional factor B3 (InterPro:IPR003340), AUX/IAA protein (InterPro:IPR003311), Auxin response factor (InterPro:IPR010525); BEST Arabidopsis thaliana protein match is: auxin response factor 19 (TAIR:AT1G19220.1); Has 2568 Blast hits to 2208 proteins in 92 species: Archae - 0; Bacteria - 11; Metazoa - 4; Fungi - 3; Plants - 2536; Viruses - 0; Other Eukaryotes - 14 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    6886669..6891404
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_101840.3 → NP_173414.1  Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_173414.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A5YYU1, A5YYU8, A5YYW1, A5YYW2, O64965, P93024, Q33DU8, Q9FXI3
    UniProtKB/TrEMBL
    A0A178W993, A0A5S9V5Z9
    Conserved Domains (3) summary
    smart01019
    Location:158 → 259
    B3; B3 DNA binding domain
    pfam02309
    Location:805 → 873
    AUX_IAA; AUX/IAA family
    pfam06507
    Location:290 → 367
    Auxin_resp; Auxin response factor

  2. NM_001332415.1 → NP_001321214.1  Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8AQ60
    Conserved Domains (3) summary
    smart01019
    Location:147 → 248
    B3; B3 DNA binding domain
    pfam02309
    Location:794 → 862
    AUX_IAA; AUX/IAA family
    pfam06507
    Location:279 → 356
    Auxin_resp; Auxin response factor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P93024.3

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