WRKY4 WRKY DNA-binding protein 4 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: WRKY4
Official Full Name: WRKY DNA-binding protein 4
Primary source: TAIR:AT1G13960
Locus tag: AT1G13960
See related: Araport:AT1G13960
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F16A14.18; WRKY DNA-binding protein 4
Summary: Encodes WRKY DNA-binding protein 4 (WRKY4).
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Genomic context

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See WRKY4 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 4

Sequence:: Chromosome: 1; NC_003070.9 (4776283..4779420)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

CRISPR/Cas9-mediated mutagenesis of WRKY3 and WRKY4 function decreases salt and Me-JA stress tolerance in Arabidopsis thaliana.
Title: CRISPR/Cas9-mediated mutagenesis of WRKY3 and WRKY4 function decreases salt and Me-JA stress tolerance in Arabidopsis thaliana.
Data support that WRKY4 function as transcription factors, have a positive role in plant resistance to necrotrophic pathogens , and has a negative effect on plant resistance to biotrophic pathogens.
Title: Roles of Arabidopsis WRKY3 and WRKY4 transcription factors in plant responses to pathogens.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001332105.1

Supported by ESTs:

NM_101262.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables transcription cis-regulatory region binding	IDA Inferred from Direct Assay more info	PubMed
enables transcription cis-regulatory region binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of defense response to bacterium	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of defense response to fungus	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to ethylene	IDA Inferred from Direct Assay more info	PubMed
involved_in response to jasmonic acid	IDA Inferred from Direct Assay more info	PubMed
involved_in response to salicylic acid	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within response to salt stress	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: WRKY DNA-binding protein 4

NP_001318999.1

WRKY DNA-binding protein 4 (WRKY4); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, DNA-dependent; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: DNA-binding WRKY (InterPro:IPR003657); BEST Arabidopsis thaliana protein match is: WRKY DNA-binding protein 3 (TAIR:AT2G03340.1); Has 5891 Blast hits to 3196 proteins in 226 species: Archae - 0; Bacteria - 0; Metazoa - 44; Fungi - 6; Plants - 5778; Viruses - 0; Other Eukaryotes - 63 (source: NCBI BLink).

NP_172849.1

WRKY DNA-binding protein 4 (WRKY4); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, DNA-dependent; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: DNA-binding WRKY (InterPro:IPR003657); BEST Arabidopsis thaliana protein match is: WRKY DNA-binding protein 3 (TAIR:AT2G03340.1); Has 5876 Blast hits to 3214 proteins in 234 species: Archae - 0; Bacteria - 0; Metazoa - 44; Fungi - 17; Plants - 5749; Viruses - 0; Other Eukaryotes - 66 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

4776283..4779420

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_101262.3 → NP_172849.1 WRKY DNA-binding protein 4 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_172849.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q93WN8, Q9LMG1, Q9XI90

UniProtKB/TrEMBL

A0A5S9UAZ3, A0A654EB63

Conserved Domains (1) summary

smart00774
Location:408 → 465

WRKY; DNA binding domain
NM_001332105.1 → NP_001318999.1 WRKY DNA-binding protein 4 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A2H1ZEB2

Conserved Domains (1) summary

smart00774
Location:255 → 312

WRKY; DNA binding domain