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NP1 NPK1-related protein kinase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837421, updated on 18-Sep-2024

Summary

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Official Symbol
NP1
Official Full Name
NPK1-related protein kinase 1
Primary source
TAIR:AT1G09000
Locus tag
AT1G09000
See related
Araport:AT1G09000
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ANP1; F7G19.13; F7G19_13; MAP KINASE KINASE KINASE 1; MAPKKK1; NPK1-related protein kinase 1
Summary
NPK1-related protein kinase 1S
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Genomic context

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See NP1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
17
Sequence:
Chromosome: 1; NC_003070.9 (2891019..2895182)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene AP2/B3-like transcriptional factor family protein Neighboring gene plant glycogenin-like starch initiation protein 5 Neighboring gene glycoside hydrolase family 2 protein Neighboring gene sucrose nonfermenting-like protein Neighboring gene nuclear factor Y, subunit B4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The intracellular ROS accumulation in elicitor-induced immunity requires the multiple organelle-targeted Arabidopsis NPK1-related protein kinases. Marti L, et al. Plant Cell Environ, 2021 Mar. PMID 33314180
  2. An Arabidopsis mitogen-activated protein kinase kinase kinase gene family encodes essential positive regulators of cytokinesis. Krysan PJ, et al. Plant Cell, 2002 May. PMID 12034900, Free PMC Article
  3. Possible involvement of differential splicing in regulation of the activity of Arabidopsis ANP1 that is related to mitogen-activated protein kinase kinase kinases (MAPKKKs). Nishihama R, et al. Plant J, 1997 Jul. PMID 9263451
  4. Phosphorylation of a mitotic kinesin-like protein and a MAPKKK by cyclin-dependent kinases (CDKs) is involved in the transition to cytokinesis in plants. Sasabe M, et al. Proc Natl Acad Sci U S A, 2011 Oct 25. PMID 22006334, Free PMC Article
  5. Functional analysis of oxidative stress-activated mitogen-activated protein kinase cascade in plants. Kovtun Y, et al. Proc Natl Acad Sci U S A, 2000 Mar 14. PMID 10717008, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The intracellular ROS accumulation in elicitor-induced immunity requires the multiple organelle-targeted Arabidopsis NPK1-related protein kinases.
    Title: The intracellular ROS accumulation in elicitor-induced immunity requires the multiple organelle-targeted Arabidopsis NPK1-related protein kinases.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_100771.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables MAP kinase kinase kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity HDA PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within MAPK cascade ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
acts_upstream_of_or_within flower development IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within protein autophosphorylation HDA PubMed 
acts_upstream_of_or_within response to oxidative stress IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
NPK1-related protein kinase 1
NP_563832.2
  • NPK1-related protein kinase 1 (NP1); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009), Mitogen activated protein kinase kinase kinase 3 (InterPro:IPR015748), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: NPK1-related protein kinase 2 (TAIR:AT1G54960.1); Has 134800 Blast hits to 132536 proteins in 4716 species: Archae - 154; Bacteria - 14967; Metazoa - 50642; Fungi - 13331; Plants - 33399; Viruses - 553; Other Eukaryotes - 21754 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    2891019..2895182
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001331801.1 → NP_001323260.1  NPK1-related protein kinase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178WGG3, A0A1P8AWJ5

  2. NM_100771.4 → NP_563832.2  NPK1-related protein kinase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_563832.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O04030, O22039, O22040, Q8GZ05
    UniProtKB/TrEMBL
    A0A178WFH4
    Conserved Domains (2) summary
    smart00220
    Location:69 → 331
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06606
    Location:68 → 331
    STKc_MAPKKK; Catalytic domain of the Serine/Threonine Kinase, Mitogen-Activated Protein Kinase Kinase Kinase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O22040.2

Gene LinkOut

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