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FATB fatty acyl-ACP thioesterases B [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837372, updated on 18-Sep-2024

Summary

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Official Symbol
FATB
Official Full Name
fatty acyl-ACP thioesterases B
Primary source
TAIR:AT1G08510
Locus tag
AT1G08510
See related
Araport:AT1G08510
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
fatty acyl-ACP thioesterases B; T27G7.19; T27G7_19
Summary
Encodes an acyl-acyl carrier protein thioesterase. Hydrolyzes primarily saturated acyl-ACPs with chain lengths that vary between 8 and 18 carbons. Involved in saturated fatty acid synthesis. Nuclear-encoded, plastid-targeted globular protein that is functional as dimer.
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Genomic context

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See FATB in Genome Data Viewer
Location:
chromosome: 1
Exon count:
6
Sequence:
Chromosome: 1; NC_003070.9 (2691062..2694547, complement)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene succinate dehydrogenase subunit Neighboring gene chloroplastic NIFS-like cysteine desulfurase Neighboring gene early nodulin-like protein 18 Neighboring gene ALBINA 1 Neighboring gene chitinase-like protein Neighboring gene RNApolymerase sigma subunit 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Disruption of the FATB gene in Arabidopsis demonstrates an essential role of saturated fatty acids in plant growth. Bonaventure G, et al. Plant Cell, 2003 Apr. PMID 12671095, Free PMC Article
  2. Genome-Wide Association Study in Arabidopsis thaliana of Natural Variation in Seed Oil Melting Point: A Widespread Adaptive Trait in Plants. Branham SE, et al. J Hered, 2016 May. PMID 26865732, Free PMC Article
  3. Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases. Salas JJ, et al. Arch Biochem Biophys, 2002 Jul 1. PMID 12061798
  4. A structural model of the plant acyl-acyl carrier protein thioesterase FatB comprises two helix/4-stranded sheet domains, the N-terminal domain containing residues that affect specificity and the C-terminal domain containing catalytic residues. Mayer KM, et al. J Biol Chem, 2005 Feb 4. PMID 15531590
  5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. FAD2 and FATB may have influenced the adaptive evolution of seed oil composition to optimize seed oil melting point relative to germination temperatures
    Title: Genome-Wide Association Study in Arabidopsis thaliana of Natural Variation in Seed Oil Melting Point: A Widespread Adaptive Trait in Plants.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

NM_100724.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables acyl carrier activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables fatty acyl-[ACP] hydrolase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within fatty acid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in plastid TAS
Traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
fatty acyl-ACP thioesterases B
NP_172327.1
  • fatty acyl-ACP thioesterases B (FATB); CONTAINS InterPro DOMAIN/s: Acyl-ACP-thioesterase, N-terminal domain (InterPro:IPR021113), Acyl-ACP thioesterase (InterPro:IPR002864); BEST Arabidopsis thaliana protein match is: fatA acyl-ACP thioesterase (TAIR:AT3G25110.1); Has 1275 Blast hits to 1274 proteins in 533 species: Archae - 0; Bacteria - 944; Metazoa - 0; Fungi - 0; Plants - 322; Viruses - 0; Other Eukaryotes - 9 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    2691062..2694547 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_100724.3 → NP_172327.1  fatty acyl-ACP thioesterases B [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_172327.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q42558, Q42562, Q9SJE2
    UniProtKB/TrEMBL
    A0A178W8J1, A0A5S9TC41, A0A654E7X4
    Conserved Domains (1) summary
    PLN02370
    Location:1 → 412
    PLN02370; acyl-ACP thioesterase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SJE2.1

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