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ACX3 acyl-CoA oxidase 3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 837140, updated on 18-Sep-2024

Summary

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Official Symbol
ACX3
Official Full Name
acyl-CoA oxidase 3
Primary source
TAIR:AT1G06290
Locus tag
AT1G06290
See related
Araport:AT1G06290
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
acyl-CoA oxidase 3; ATACX3
Summary
Encodes an acyl-CoA oxidase with specificity for medium chain fatty acids.
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Genomic context

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See ACX3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
13
Sequence:
Chromosome: 1; NC_003070.9 (1922208..1926278)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene LOB domain-containing protein 2 Neighboring gene acyl-CoA oxidase 6 Neighboring gene uncharacterized protein Neighboring gene Heavy metal transport/detoxification superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mutations in Arabidopsis acyl-CoA oxidase genes reveal distinct and overlapping roles in beta-oxidation. Adham AR, et al. Plant J, 2005 Mar. PMID 15743450
  2. CATALASE2 functions for seedling postgerminative growth by scavenging H(2) O(2) and stimulating ACX2/3 activity in Arabidopsis. Liu WC, et al. Plant Cell Environ, 2017 Nov. PMID 28722222
  3. Peroxisomal Acyl-CoA oxidase 4 activity differs between Arabidopsis accessions. Khan BR, et al. Plant Mol Biol, 2012 Jan. PMID 22048901
  4. Identification of ubiquitinated proteins in Arabidopsis. Manzano C, et al. Plant Mol Biol, 2008 Sep. PMID 18535787
  5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. CAT2 functions in early seedling growth by scavenging hydrogen peroxide and stimulating ACX2/3 activity.
    Title: CATALASE2 functions for seedling postgerminative growth by scavenging H(2) O(2) and stimulating ACX2/3 activity in Arabidopsis.
  2. Data show that acx3acx4 Columbia (Col) and acx1acx3acx4 (Col) mutants are viable and that enzyme activity in these mutants is significantly reduced on a range of substrates compared to wild type.
    Title: Peroxisomal Acyl-CoA oxidase 4 activity differs between Arabidopsis accessions.
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Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_100511.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables FAD binding IEA
Inferred from Electronic Annotation
more info
  
enables acyl-CoA oxidase activity TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within fatty acid beta-oxidation TAS
Traceable Author Statement
more info
 PubMed 
involved_in fatty acid beta-oxidation using acyl-CoA oxidase IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within medium-chain fatty acid metabolic process TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region HDA PubMed 

General protein information

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Preferred Names
acyl-CoA oxidase 3
NP_172119.1
  • acyl-CoA oxidase 3 (ACX3); FUNCTIONS IN: acyl-CoA oxidase activity; INVOLVED IN: medium-chain fatty acid metabolic process, fatty acid beta-oxidation; LOCATED IN: peroxisome; EXPRESSED IN: male gametophyte, guard cell, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal (InterPro:IPR013764), Acyl-CoA oxidase/dehydrogenase, type 1 (InterPro:IPR006090), Acyl-CoA dehydrogenase/oxidase (InterPro:IPR009100), Acyl-CoA oxidase (InterPro:IPR012258), Acyl-CoA oxidase/dehydrogenase, central domain (InterPro:IPR006091), Acyl-CoA oxidase, C-terminal (InterPro:IPR002655), Acyl-CoA dehydrogenase/oxidase C-terminal (InterPro:IPR009075); BEST Arabidopsis thaliana protein match is: acyl-CoA oxidase 6 (TAIR:AT1G06310.1); Has 12520 Blast hits to 12510 proteins in 1399 species: Archae - 229; Bacteria - 8347; Metazoa - 1502; Fungi - 589; Plants - 297; Viruses - 0; Other Eukaryotes - 1556 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    1922208..1926278
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_100511.3 → NP_172119.1  acyl-CoA oxidase 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_172119.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P0CZ23, Q9C839, Q9LKX5, Q9LLH9, Q9LMI8, Q9M7X6
    UniProtKB/TrEMBL
    A0A178WDE4, A0A7G2DR42
    Conserved Domains (1) summary
    PLN02312
    Location:1 → 675
    PLN02312; acyl-CoA oxidase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0CZ23.1

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