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CYP86A1 cytochrome P450, family 86, subfamily A, polypeptide 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 836003, updated on 18-Sep-2024

Summary

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Official Symbol
CYP86A1
Official Full Name
cytochrome P450, family 86, subfamily A, polypeptide 1
Primary source
TAIR:AT5G58860
Locus tag
AT5G58860
See related
Araport:AT5G58860
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
''cytochrome P450; CYP86; cytochrome P450; family 86; HORST; hydroxylase of root suberized tissue; K19M22.14; K19M22_14; polypeptide 1; polypeptide 1''; subfamily A
Summary
Encodes a member of the CYP86A subfamily of cytochrome p450 genes. Expressed significantly only in root tissue.
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Genomic context

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See CYP86A1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
2
Sequence:
Chromosome: 5; NC_003076.8 (23765791..23768111, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Subtilase family protein Neighboring gene myb domain protein 119 Neighboring gene FTSH protease 9 Neighboring gene LRR protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Arabidopsis cytochrome P450 CYP86A1 encodes a fatty acid omega-hydroxylase involved in suberin monomer biosynthesis. Höfer R, et al. J Exp Bot, 2008. PMID 18544608, Free PMC Article
  2. Identification of acyltransferases required for cutin biosynthesis and production of cutin with suberin-like monomers. Li Y, et al. Proc Natl Acad Sci U S A, 2007 Nov 13. PMID 17991776, Free PMC Article
  3. Differential expression and evolution of the Arabidopsis CYP86A subfamily. Duan H, et al. Plant Physiol, 2005 Mar. PMID 15709153, Free PMC Article
  4. The vegetative vacuole proteome of Arabidopsis thaliana reveals predicted and unexpected proteins. Carter C, et al. Plant Cell, 2004 Dec. PMID 15539469, Free PMC Article
  5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. cytochrome P450 fatty acid omega-hydroxylase CYP86A1 (At5g58860) was identified as a key enzyme for aliphatic root suberin biosynthesis in Arabidopsis.
    Title: The Arabidopsis cytochrome P450 CYP86A1 encodes a fatty acid omega-hydroxylase involved in suberin monomer biosynthesis.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Homology

NM_125276.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables alkane 1-monooxygenase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables long-chain fatty acid omega-hydroxylase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within fatty acid metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within suberin biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in plant-type vacuole HDA PubMed 

General protein information

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Preferred Names
cytochrome P450, family 86, subfamily A, polypeptide 1
NP_200694.1
  • ''cytochrome P450, family 86, subfamily A, polypeptide 1'' (CYP86A1); FUNCTIONS IN: alkane 1-monooxygenase activity, oxygen binding; INVOLVED IN: fatty acid metabolic process, suberin biosynthetic process; LOCATED IN: vacuole; EXPRESSED IN: hypocotyl, root; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: cytochrome P450, family 86, subfamily A, polypeptide 2 (TAIR:AT4G00360.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    23765791..23768111 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_125276.3 → NP_200694.1  cytochrome P450, family 86, subfamily A, polypeptide 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_200694.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P48422, Q8RXG6, Q9FIM3
    UniProtKB/TrEMBL
    A0A178UBQ8, A0A5S9YFB0, A0A654GCB6
    Conserved Domains (1) summary
    cd11064
    Location:70 → 501
    CYP86A; cytochrome P450 family 86, subfamily A
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P48422.2

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