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RPL POX (plant homeobox) family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 831745, updated on 18-Sep-2024

Summary

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Official Symbol
RPL
Official Full Name
POX (plant homeobox) family protein
Primary source
TAIR:AT5G02030
Locus tag
AT5G02030
See related
Araport:AT5G02030
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
BEL1-LIKE HOMEODOMAIN 9; BELLRINGER; BLH9; BLR; HB-6; LARSON; LSN; PENNYWISE; PNY; REPLUMLESS; T7H20.80; T7H20_80; VAAMANA; VAN
Summary
Mutant has additional lateral organs and phyllotaxy defect. Encodes a homeodomain transcription factor. Has sequence similarity to the Arabidopsis ovule development regulator Bell1. Binds directly to the AGAMOUS cis-regulatory element. Its localization to the nucleus is dependent on the coexpression of either STM or BP.
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Genomic context

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See RPL in Genome Data Viewer
Location:
chromosome: 5
Exon count:
4
Sequence:
Chromosome: 5; NC_003076.8 (395567..399125)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene RHO guanyl-nucleotide exchange factor 7 Neighboring gene E3 ubiquitin-protein ligase RLIM-like protein Neighboring gene tRNA-Gly Neighboring gene ncRNA Neighboring gene prenylated RAB acceptor 1.A1 Neighboring gene Mitochondrial glycoprotein family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The REPLUMLESS Transcription Factor Controls the Expression of the RECEPTOR-LIKE CYTOPLASMIC KINASE VI_A2 Gene Involved in Shoot and Fruit Patterning of Arabidopsis thaliana. Kenesi E, et al. Int J Mol Sci, 2024 Jul 22. PMID 39063242, Free PMC Article
  2. The transcription factor BELLRINGER modulates phyllotaxis by regulating the expression of a pectin methylesterase in Arabidopsis. Peaucelle A, et al. Development, 2011 Nov. PMID 21965608
  3. The same regulatory point mutation changed seed-dispersal structures in evolution and domestication. Arnaud N, et al. Curr Biol, 2011 Jul 26. PMID 21737279
  4. Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis. Khan M, et al. Plant Physiol, 2015 Nov. PMID 26417006, Free PMC Article
  5. Competence to respond to floral inductive signals requires the homeobox genes PENNYWISE and POUND-FOOLISH. Smith HM, et al. Curr Biol, 2004 May 4. PMID 15120075

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The REPLUMLESS Transcription Factor Controls the Expression of the RECEPTOR-LIKE CYTOPLASMIC KINASE VI_A2 Gene Involved in Shoot and Fruit Patterning of Arabidopsis thaliana.
    Title: The REPLUMLESS Transcription Factor Controls the Expression of the RECEPTOR-LIKE CYTOPLASMIC KINASE VI_A2 Gene Involved in Shoot and Fruit Patterning of Arabidopsis thaliana.
  2. The data reveal a potential mechanism by which repression of lateral organ boundary genes by PNY-PNF is essential for flowering.
    Title: Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis.
  3. NTT loss of function leads to reduced replum width and cell number, whereas increased expression promotes replum enlargement. NTT activates the homeobox gene BP, which, together with RPL, is important for replum development.
    Title: The NTT transcription factor promotes replum development in Arabidopsis fruits.
  4. These data support a role for BLR in ordering the shoot apex.
    Title: A role for BELLRINGER in cell wall development is supported by loss-of-function phenotypes.
  5. Regulation of meristem central zone integrity by PNY and PNF is crucial for vegetative and reproductive development.
    Title: Regulation of shoot meristem integrity during Arabidopsis vegetative development.
  6. SPL3, SPL4, and SPL5 function is dependent upon PNY and PNF
    Title: Regulation of the SQUAMOSA PROMOTER-BINDING PROTEIN-LIKE genes/microRNA156 module by the homeodomain proteins PENNYWISE and POUND-FOOLISH in Arabidopsis.
  7. Results report a dual function for the homeodomain transcription factor BELLRINGER (BLR) in the establishment and maintenance of the phyllotactic pattern in Arabidopsis.
    Title: The transcription factor BELLRINGER modulates phyllotaxis by regulating the expression of a pectin methylesterase in Arabidopsis.
  8. Reduced repla resembling Arabidopsis rpl mutant correlated across the Brassicaceae with a point mutation in a conserved cis-element of RPL. When introduced in Arabidopsis, this nucleotide change specifically reduced RPL expression + function in the fruit.
    Title: The same regulatory point mutation changed seed-dispersal structures in evolution and domestication.
  9. PNY and PNF act to restrict organogenesis to the peripheral zone by maintaining a boundary between the central zone and peripheral zone.
    Title: The role of PENNYWISE and POUND-FOOLISH in the maintenance of the shoot apical meristem in Arabidopsis.
  10. combined lesions in ATH1, PNY and PNF result in a full phenocopy of shoot apical meristem loss-of-function mutants.
    Title: Shoot apical meristem function in Arabidopsis requires the combined activities of three BEL1-like homeodomain proteins.
Submit: New GeneRIF Correction See all GeneRIFs (14)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_120281.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within floral whorl morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within fruit development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within internode patterning IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within maintenance of floral meristem identity IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within maintenance of inflorescence meristem identity IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within negative regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within pattern specification process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within plant organ formation IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within secondary shoot formation IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within shoot system development IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within vegetative to reproductive phase transition of meristem IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within xylem and phloem pattern formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within xylem development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
POX (plant homeobox) family protein
NP_195823.1
  • REPLUMLESS (RPL); CONTAINS InterPro DOMAIN/s: Homeobox (InterPro:IPR001356), Homeodomain-like (InterPro:IPR009057), POX (InterPro:IPR006563), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: BEL1-like homeodomain 8 (TAIR:AT2G27990.1); Has 5109 Blast hits to 5109 proteins in 341 species: Archae - 0; Bacteria - 2; Metazoa - 2052; Fungi - 344; Plants - 2481; Viruses - 0; Other Eukaryotes - 230 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    395567..399125
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_120281.3 → NP_195823.1  POX (plant homeobox) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_195823.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8H147, Q8LGJ2, Q9LZM8
    UniProtKB/TrEMBL
    A0A5S9Y1A2, A0A7G2F538
    Conserved Domains (2) summary
    smart00574
    Location:165 → 292
    POX; domain associated with HOX domains
    pfam05920
    Location:366 → 405
    Homeobox_KN; Homeobox KN domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LZM8.1

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