NAC2 NAC domain containing protein 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: NAC2
Official Full Name: NAC domain containing protein 2
Primary source: TAIR:AT5G04410
Locus tag: AT5G04410
See related: Araport:AT5G04410
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: anac078; Arabidopsis NAC domain containing protein 78; NAC domain containing protein 2; T19N18.11
Summary: NAC family member, functions as a transcriptional activator, regulates flavonoid biosynthesis under high light.
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Genomic context

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See NAC2 in Genome Data Viewer

Location:: chromosome: 5

Exon count:: 6

Sequence:: Chromosome: 5; NC_003076.8 (1243684..1246684)

Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

PI4K gamma 5 is important for the normal function of ANAC078 and PI4K gamma 5 is required for ANAC078 cleavage and proteolytic activation [ANAC078]
Title: Arabidopsis Type II Phosphatidylinositol 4-Kinase PI4Kγ5 Regulates Auxin Biosynthesis and Leaf Margin Development through Interacting with Membrane-Bound Transcription Factor ANAC078.
RPX is a negative regulator of leaf organ size. RPX binds to the promoter of genes encoding 26S proteasomal proteins in vivo, resulting in increased gene expression and proteasome activity.
Title: An upstream regulator of the 26S proteasome modulates organ size in Arabidopsis thaliana.
The transcript levels of 13 proteasome subunit genes, the protein levels of proteasomes, and the activities of the 26S proteasome in ANAC078-overexpressing Arabidopsis plants (Ox-ANAC078) and knockout ANAC078 (KO-ANAC078) mutants, was investigated.
Title: Involvement of Arabidopsis NAC transcription factor in the regulation of 20S and 26S proteasomes.
ANAC092 strongly responds to long-term salt stress that triggers senescence.
Title: A gene regulatory network controlled by the NAC transcription factor ANAC092/AtNAC2/ORE1 during salt-promoted senescence.
Molecular mechanisms underlying the cold temperature regulation of flowering time of Arabidopsis are controled by NAC2.
Title: Control of flowering time and cold response by a NAC-domain protein in Arabidopsis.
ANAC078 protein functions as a transcription factor, and is associated with expression of genes related to flavonoid biosynthesis, leading to the accumulation of anthocyanins, in response to high light stress.
Title: Arabidopsis NAC transcription factor, ANAC078, regulates flavonoid biosynthesis under high-light.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_120523.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within positive regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within regulation of flavonoid biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to high light intensity	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: NAC domain containing protein 2

NP_196061.1

NAC domain containing protein 2 (NAC2); CONTAINS InterPro DOMAIN/s: No apical meristem (NAM) protein (InterPro:IPR003441); BEST Arabidopsis thaliana protein match is: NAC domain containing protein 53 (TAIR:AT3G10500.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).