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Inositol 1,3,4-trisphosphate 5/6-kinase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 829519, updated on 18-Sep-2024

Summary

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Official Full Name
Inositol 1,3,4-trisphosphate 5/6-kinase family protein
Primary source
TAIR:AT4G33770
Locus tag
AT4G33770
See related
Araport:AT4G33770
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
3; 4-trisphosphate 5/6 kinase 2; inositol 1; ITPK2; T16L1.260; T16L1_260
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Genomic context

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Location:
chromosome: 4
Exon count:
9
Sequence:
Chromosome: 4; NC_003075.7 (16193373..16196642, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene myb-like protein X Neighboring gene tRNA synthetase class II (D, K and N) family protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ATP phosphoribosyltransferase regulatory subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis inositol 1,3,4-trisphosphate 5/6 kinase 2 is required for seed coat development. Tang Y, et al. Acta Biochim Biophys Sin (Shanghai), 2013 Jul. PMID 23595027
  2. INOSITOL (1,3,4) TRIPHOSPHATE 5/6 KINASE1-dependent inositol polyphosphates regulate auxin responses in Arabidopsis. Laha NP, et al. Plant Physiol, 2022 Nov 28. PMID 36124979, Free PMC Article
  3. Arabidopsis ITPK1 and ITPK2 Have an Evolutionarily Conserved Phytic Acid Kinase Activity. Laha D, et al. ACS Chem Biol, 2019 Oct 18. PMID 31525024
  4. Arabidopsis thaliana inositol 1,3,4-trisphosphate 5/6-kinase 4 (AtITPK4) is an outlier to a family of ATP-grasp fold proteins from Arabidopsis. Sweetman D, et al. FEBS Lett, 2007 Sep 4. PMID 17698066
  5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ITPK2 protein phosphorylates phytic acid to yield inositol heptakisphosphate.
    Title: Arabidopsis ITPK1 and ITPK2 Have an Evolutionarily Conserved Phytic Acid Kinase Activity.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001085021.2
NM_001342232.1
NM_119535.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables inositol-1,3,4-trisphosphate 5-kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables inositol-1,3,4-trisphosphate 5-kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables inositol-1,3,4-trisphosphate 6-kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables inositol-1,3,4-trisphosphate 6-kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables inositol-3,4,5,6-tetrakisphosphate 1-kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables inositol-3,4,5,6-tetrakisphosphate 1-kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in auxin-activated signaling pathway IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in inositol trisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in seed coat development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Inositol 1,3,4-trisphosphate 5/6-kinase family protein
NP_001078490.1
  • Inositol 1,3,4-trisphosphate 5/6-kinase family protein; FUNCTIONS IN: inositol or phosphatidylinositol kinase activity, magnesium ion binding, inositol-1,3,4-trisphosphate 5/6-kinase activity, inositol tetrakisphosphate 1-kinase activity, ATP binding; INVOLVED IN: inositol trisphosphate metabolic process; LOCATED IN: intracellular; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Inositol-tetrakisphosphate 1-kinase (InterPro:IPR017427), Inositol 1, 3, 4-trisphosphate 56-kinase (InterPro:IPR008656); BEST Arabidopsis thaliana protein match is: Inositol 1,3,4-trisphosphate 5/6-kinase family protein (TAIR:AT4G08170.2); Has 392 Blast hits to 387 proteins in 76 species: Archae - 0; Bacteria - 0; Metazoa - 96; Fungi - 0; Plants - 249; Viruses - 0; Other Eukaryotes - 47 (source: NCBI BLink).
NP_195103.3
  • Inositol 1,3,4-trisphosphate 5/6-kinase family protein; FUNCTIONS IN: inositol or phosphatidylinositol kinase activity, magnesium ion binding, inositol-1,3,4-trisphosphate 5/6-kinase activity, inositol tetrakisphosphate 1-kinase activity, ATP binding; INVOLVED IN: inositol trisphosphate metabolic process; LOCATED IN: intracellular; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Inositol-tetrakisphosphate 1-kinase (InterPro:IPR017427), Inositol 1, 3, 4-trisphosphate 56-kinase (InterPro:IPR008656); BEST Arabidopsis thaliana protein match is: Inositol 1,3,4-trisphosphate 5/6-kinase family protein (TAIR:AT4G08170.2); Has 392 Blast hits to 387 proteins in 75 species: Archae - 0; Bacteria - 0; Metazoa - 96; Fungi - 0; Plants - 249; Viruses - 0; Other Eukaryotes - 47 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    16193373..16196642 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_119535.5 → NP_195103.3  Inositol 1,3,4-trisphosphate 5/6-kinase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_195103.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O81893, Q058I3
    UniProtKB/TrEMBL
    A0A178V3P3
    Conserved Domains (1) summary
    PLN02941
    Location:80 → 384
    PLN02941; inositol-tetrakisphosphate 1-kinase

  2. NM_001342232.1 → NP_001328707.1  Inositol 1,3,4-trisphosphate 5/6-kinase family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178V2A8, A0A1P8B5H0, A0A384KFJ1

  3. NM_001085021.2 → NP_001078490.1  Inositol 1,3,4-trisphosphate 5/6-kinase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001078490.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A8MRH2
    Conserved Domains (1) summary
    PLN02941
    Location:12 → 291
    PLN02941; inositol-tetrakisphosphate 1-kinase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O81893.3

Gene LinkOut

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