ATCES1 Alkaline phytoceramidase (aPHC) [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: ATCES1
Official Full Name: Alkaline phytoceramidase (aPHC)
Primary source: TAIR:AT4G22330
Locus tag: AT4G22330
See related: Araport:AT4G22330
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: T10I14.160; T10I14_160
Summary: Encodes AtCES1 for Acyl-CoA independent ceramide synthase.
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Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

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NM_118359.4

Function	Evidence Code	Pubs
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within autophagy	IDA Inferred from Direct Assay more info	PubMed
involved_in ceramide metabolic process	IEA Inferred from Electronic Annotation more info
involved_in defense response to bacterium	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within defense response to other organism	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within leaf senescence	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within positive regulation of autophagy	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of stomatal closure	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to abscisic acid	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to molecule of fungal origin	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to nutrient levels	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to salt stress	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within sphingolipid biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in wax biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	HDA more info	PubMed
located_in Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
located_in endoplasmic reticulum	HDA more info	PubMed
located_in endoplasmic reticulum	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed

NP_567660.1

ATCES1; FUNCTIONS IN: catalytic activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; INVOLVED IN: ceramide metabolic process; LOCATED IN: endoplasmic reticulum, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ceramidase (InterPro:IPR008901); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).