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ANL2 Homeobox-leucine zipper family protein / lipid-binding START domain-containing protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 828022, updated on 18-Sep-2024

Summary

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Official Symbol
ANL2
Official Full Name
Homeobox-leucine zipper family protein / lipid-binding START domain-containing protein
Primary source
TAIR:AT4G00730
Locus tag
AT4G00730
See related
Araport:AT4G00730
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AHDP; ANTHOCYANINLESS 2; ARABIDOPSIS THALIANA HOMEODOMAIN PROTEIN; F6N23.10; F6N23_10; HOMEODOMAIN PROTEIN AHDP
Summary
Encodes a homeodomain protein of the HD-GLABRA2 group. Involved in the accumulation of anthocyanin and in root development
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Genomic context

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See ANL2 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
9
Sequence:
Chromosome: 4; NC_003075.7 (299261..304612, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene BR-signaling kinase 3 Neighboring gene shaggy-like protein kinase 32 Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phenotypic screening of Arabidopsis T-DNA insertion lines for cell wall mechanical properties revealed ANTHOCYANINLESS2, a cell wall-related gene. Mabuchi A, et al. J Plant Physiol, 2016 Feb 1. PMID 26720211
  2. Characterization of root cells of anl2 mutant in Arabidopsis thaliana. Kubo H, et al. Plant Sci, 2011 May. PMID 21421418
  3. ANTHOCYANINLESS2, a homeobox gene affecting anthocyanin distribution and root development in Arabidopsis. Kubo H, et al. Plant Cell, 1999 Jul. PMID 10402424, Free PMC Article
  4. Pleiotropic phenotypes of the sticky peel mutant provide new insight into the role of CUTIN DEFICIENT2 in epidermal cell function in tomato. Nadakuduti SS, et al. Plant Physiol, 2012 Jul. PMID 22623518, Free PMC Article
  5. AIL and HDG proteins act antagonistically to control cell proliferation. Horstman A, et al. Development, 2015 Feb 1. PMID 25564655

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ANTHOCYANINLESS2 (ANL2), a gene involved in the regulation of cell wall mechanical properties, was identified.
    Title: Phenotypic screening of Arabidopsis T-DNA insertion lines for cell wall mechanical properties revealed ANTHOCYANINLESS2, a cell wall-related gene.
  2. In plants with an ANL2 gene mutation, extra (intervening) cells develop from epidermal cells but become cortical in nature, and expression of some epidermis-specific genes is abnormal.
    Title: Characterization of root cells of anl2 mutant in Arabidopsis thaliana.
Submit: New GeneRIF Correction

General gene information

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Markers

NM_001125435.1
NM_116298.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables lipid binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription cis-regulatory region binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within anthocyanin accumulation in tissues in response to UV light IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within cutin biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within plant-type cell wall modification IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within root development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within root hair cell differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Homeobox-leucine zipper family protein / lipid-binding START domain-containing protein
NP_001118907.1
  • ANTHOCYANINLESS 2 (ANL2); FUNCTIONS IN: transcription regulator activity, sequence-specific DNA binding transcription factor activity; INVOLVED IN: root development, anthocyanin accumulation in tissues in response to UV light; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Homeobox, conserved site (InterPro:IPR017970), Homeobox (InterPro:IPR001356), Homeodomain-like (InterPro:IPR009057), Lipid-binding START (InterPro:IPR002913), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: homeodomain GLABROUS 1 (TAIR:AT3G61150.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_567183.2
  • ANTHOCYANINLESS 2 (ANL2); FUNCTIONS IN: transcription regulator activity, sequence-specific DNA binding transcription factor activity; INVOLVED IN: root development, anthocyanin accumulation in tissues in response to UV light; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Homeobox (InterPro:IPR001356), Homeobox, conserved site (InterPro:IPR017970), Homeodomain-like (InterPro:IPR009057), Lipid-binding START (InterPro:IPR002913), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: homeodomain GLABROUS 1 (TAIR:AT3G61150.1); Has 12660 Blast hits to 12608 proteins in 595 species: Archae - 0; Bacteria - 0; Metazoa - 9962; Fungi - 223; Plants - 2228; Viruses - 1; Other Eukaryotes - 246 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    299261..304612 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_116298.4 → NP_567183.2  Homeobox-leucine zipper family protein / lipid-binding START domain-containing protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_567183.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O65281, P93041, Q0WV12, Q9SWZ6
    UniProtKB/TrEMBL
    A0A5S9XPH6
    Conserved Domains (3) summary
    cd08875
    Location:319 → 542
    START_ArGLABRA2_like; C-terminal lipid-binding START domain of the Arabidopsis homeobox protein GLABRA 2 and related proteins
    COG5576
    Location:99 → 209
    COG5576; Homeodomain-containing transcription factor [Transcription]
    pfam00046
    Location:137 → 190
    Homeobox; Homeobox domain

  2. NM_001125435.1 → NP_001118907.1  Homeobox-leucine zipper family protein / lipid-binding START domain-containing protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001118907.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B3H591
    Conserved Domains (3) summary
    cd08875
    Location:319 → 542
    START_ArGLABRA2_like; C-terminal lipid-binding START domain of the Arabidopsis homeobox protein GLABRA 2 and related proteins
    COG5576
    Location:99 → 209
    COG5576; Homeodomain-containing transcription factor [Transcription]
    pfam00046
    Location:137 → 190
    Homeobox; Homeobox domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0WV12.1

Gene LinkOut

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