HDG1 homeodomain GLABROUS 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: HDG1
Official Full Name: homeodomain GLABROUS 1
Primary source: TAIR:AT3G61150
Locus tag: AT3G61150
See related: Araport:AT3G61150
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: HD-GL2-1; homeodomain GLABROUS 1; HOMEODOMAIN-GLABRA2 1
Summary: Encodes a homeobox-leucine zipper family protein belonging to the HD-ZIP IV family.
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Genomic context

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See HDG1 in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 9

Sequence:: Chromosome: 3; NC_003074.8 (22630331..22635155)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data suggest that presence of mediator complex subunits MED10a, MED28, and MED32 or changes in redox state affect DNA-binding capacity of GeBPL (GLABROUS1/GL1 enhancer-binding protein-like) at likely GLABROUS1/GL1 promoter.
Title: Biochemical and redox characterization of the mediator complex and its associated transcription factor GeBPL, a GLABROUS1 enhancer binding protein.
Rice and Arabidopsis CFL1 negatively regulate cuticle development by affecting the function of HDG1, which regulates the downstream genes BDG and FDH.
Title: CFL1, a WW domain protein, regulates cuticle development by modulating the function of HDG1, a class IV homeodomain transcription factor, in rice and Arabidopsis.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_115979.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info
enables lipid binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables transcription cis-regulatory region binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_positive_effect cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within_positive_effect cuticle development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within maintenance of floral organ identity	IGI Inferred from Genetic Interaction more info	PubMed
involved_in maintenance of floral organ identity	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: homeodomain GLABROUS 1

NP_191674.1

homeodomain GLABROUS 1 (HDG1); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, DNA-dependent, regulation of transcription; LOCATED IN: nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Homeobox, conserved site (InterPro:IPR017970), Homeobox (InterPro:IPR001356), Homeodomain-like (InterPro:IPR009057), Lipid-binding START (InterPro:IPR002913), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: Homeobox-leucine zipper family protein / lipid-binding START domain-containing protein (TAIR:AT4G00730.1); Has 11756 Blast hits to 11371 proteins in 530 species: Archae - 0; Bacteria - 4; Metazoa - 8768; Fungi - 189; Plants - 2580; Viruses - 0; Other Eukaryotes - 215 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

22630331..22635155

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_115979.5 → NP_191674.1 homeodomain GLABROUS 1 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_191674.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9LFW5, Q9M2E8

UniProtKB/TrEMBL

A0A178V5Q4, A0A7G2EUF5

Conserved Domains (3) summary

cd08875
Location:314 → 537

START_ArGLABRA2_like; C-terminal lipid-binding START domain of the Arabidopsis homeobox protein GLABRA 2 and related proteins

COG5576
Location:69 → 185

COG5576; Homeodomain-containing transcription factor [Transcription]

pfam00046
Location:113 → 166

Homeobox; Homeobox domain