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AL3 alfin-like 3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 823316, updated on 18-Sep-2024

Summary

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Official Symbol
AL3
Official Full Name
alfin-like 3
Primary source
TAIR:AT3G42790
Locus tag
AT3G42790
See related
Araport:AT3G42790
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
alfin-like 3
Summary
Encodes a member of the Alfin1-like family of nuclear-localized PHD (plant homeodomain) domain containing proteins. All AL proteins except AL3 bind to di- or trimethylated histone H3 (H3K4me3/2). Members of this family include: AT5G05610 (AL1), AT3G11200 (AL2), AT3G42790 (AL3), AT5G26210 (AL4), AT5G20510 (AL5), AT2G02470 (AL6), AT1G14510 (AL7).
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Genomic context

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See AL3 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
5
Sequence:
Chromosome: 3; NC_003074.8 (14877890..14879792, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene zinc finger MYM-type-like protein Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. SUMO protease FUG1, histone reader AL3 and chromodomain protein LHP1 are integral to repeat expansion-induced gene silencing in Arabidopsis thaliana. Sureshkumar S, et al. Nat Plants, 2024 May. PMID 38641663
  2. The Alfin-like homeodomain finger protein AL5 suppresses multiple negative factors to confer abiotic stress tolerance in Arabidopsis. Wei W, et al. Plant J, 2015 Mar. PMID 25619813
  3. Arabidopsis ING and Alfin1-like protein families localize to the nucleus and bind to H3K4me3/2 via plant homeodomain fingers. Lee WY, et al. Plant J, 2009 May. PMID 19154204
  4. A PXY-Mediated Transcriptional Network Integrates Signaling Mechanisms to Control Vascular Development in Arabidopsis. Smit ME, et al. Plant Cell, 2020 Feb. PMID 31806676, Free PMC Article
  5. Transcriptional regulation of nitrogen-associated metabolism and growth. Gaudinier A, et al. Nature, 2018 Nov. PMID 30356219

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. SUMO protease FUG1, histone reader AL3 and chromodomain protein LHP1 are integral to repeat expansion-induced gene silencing in Arabidopsis thaliana.
    Title: SUMO protease FUG1, histone reader AL3 and chromodomain protein LHP1 are integral to repeat expansion-induced gene silencing in Arabidopsis thaliana.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_114147.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables histone binding IEA
Inferred from Electronic Annotation
more info
  
NOT enables methylated histone binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables transcription cis-regulatory region binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
alfin-like 3
NP_189865.1
  • alfin-like 3 (AL3); CONTAINS InterPro DOMAIN/s: Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Zinc finger, PHD-type (InterPro:IPR001965), Protein of unknown function DUF3594 (InterPro:IPR021998), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: alfin-like 5 (TAIR:AT5G20510.1); Has 1689 Blast hits to 1654 proteins in 192 species: Archae - 0; Bacteria - 0; Metazoa - 785; Fungi - 353; Plants - 465; Viruses - 0; Other Eukaryotes - 86 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    14877890..14879792 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_114147.5 → NP_189865.1  alfin-like 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_189865.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9M2B4
    UniProtKB/TrEMBL
    A0A178VCG6, A0A5S9XHC4, A0A654FC80
    Conserved Domains (2) summary
    cd15613
    Location:196 → 246
    PHD_AL_plant; PHD finger found in plant Alfin1-like (AL) proteins
    pfam12165
    Location:13 → 140
    Alfin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9M2B4.1

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