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PRP40C [ Arabidopsis thaliana (thale cress) ]

Gene ID: 821521, updated on 22-Aug-2024

Summary

Official Symbol
PRP40C
Primary source
Araport:AT3G19840
Locus tag
AT3G19840
See related
TAIR:AT3G19840
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATPRP40C; pre-mRNA-processing protein 40C
Summary
Binds the carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II and functions as a scaffold for RNA processing machineries.
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Genomic context

See PRP40C in Genome Data Viewer
Location:
chromosome: 3
Exon count:
13
Sequence:
Chromosome: 3; NC_003074.8 (6890988..6897510)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene BTB/POZ domain protein, putative (DUF177) Neighboring gene cell elongation protein / DWARF1 / DIMINUTO (DIM) Neighboring gene Calcium-dependent lipid-binding (CaLB domain) family protein Neighboring gene ncRNA Neighboring gene Phototropic-responsive NPH3 family protein Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

NM_112874.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables RNA polymerase binding IDA
Inferred from Direct Assay
more info
PubMed 
enables transcription coregulator activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within RNA splicing IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
 

General protein information

Preferred Names
pre-mRNA-processing protein 40C
NP_188618.3
  • pre-mRNA-processing protein 40C (PRP40C); CONTAINS InterPro DOMAIN/s: FF domain (InterPro:IPR002713), WW/Rsp5/WWP (InterPro:IPR001202); BEST Arabidopsis thaliana protein match is: pre-mRNA-processing protein 40A (TAIR:AT1G44910.2); Has 7513 Blast hits to 5748 proteins in 436 species: Archae - 33; Bacteria - 336; Metazoa - 3654; Fungi - 967; Plants - 481; Viruses - 7; Other Eukaryotes - 2035 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    6890988..6897510
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_112874.4NP_188618.3  pre-mRNA-processing protein 40C [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_188618.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8GZ66, Q9LT25
    UniProtKB/TrEMBL
    A0A5S9XDS4
    Conserved Domains (5) summary
    COG5104
    Location:249625
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:299328
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    pfam00397
    Location:249274
    WW; WW domain
    pfam01846
    Location:457506
    FF; FF domain
    pfam08347
    Location:103201
    CTNNB1_binding; N-terminal CTNNB1 binding