NPC5 non-specific phospholipase C5 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: NPC5
Official Full Name: non-specific phospholipase C5
Primary source: TAIR:AT3G03540
Locus tag: AT3G03540
See related: Araport:AT3G03540
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: non-specific phospholipase C5; T21P5.4
Summary: Encodes a nonspecific phospholipase C. Located in the cytosol. Involved in the conversion of phospholipids to glycolipids under phosphate deprivation conditions.
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Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

NPC5 mediates lateral root development in response to salt stress.
Title: Non-specific phospholipase C5 and diacylglycerol promote lateral root development under mild salt stress in Arabidopsis.
Non-specific phospholipase C5 (NPC5 or At3G03540) is critical for phospholipid degradation and digalactosyldiacylglycerol accumulation in Arabidopsis leaves during phosphate limitation.
Title: Phospholipase C5 (NPC5) is involved in galactolipid accumulation during phosphate limitation in leaves of Arabidopsis.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_111225.2

Function	Evidence Code	Pubs
enables phosphatidylcholine phospholipase C activity	IEA Inferred from Electronic Annotation more info
enables phospholipase C activity	IDA Inferred from Direct Assay more info	PubMed
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within cellular response to phosphate starvation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within glycolipid biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within phospholipid catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	ISM Inferred from Sequence Model more info

NP_566207.1

non-specific phospholipase C5 (NPC5); CONTAINS InterPro DOMAIN/s: Phosphoesterase (InterPro:IPR007312); BEST Arabidopsis thaliana protein match is: non-specific phospholipase C4 (TAIR:AT3G03530.1); Has 2077 Blast hits to 2037 proteins in 379 species: Archae - 32; Bacteria - 1720; Metazoa - 0; Fungi - 127; Plants - 154; Viruses - 0; Other Eukaryotes - 44 (source: NCBI BLink).