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MYB5 myb domain protein 5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 820556, updated on 18-Sep-2024

Summary

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Official Symbol
MYB5
Official Full Name
myb domain protein 5
Primary source
TAIR:AT3G13540
Locus tag
AT3G13540
See related
Araport:AT3G13540
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ABC transporter of the mitochondrion 2; ATM2; ATMYB5; myb domain protein 5
Summary
Encodes a member of the MYB family of transcriptional regulators. MYB5 act as a negative regulator of trichome branching and play a role in the correct formation of the seed coat and possibly the formation the underlying endosperm layers. Loss of function mutations have defects in seed coat mucilage and columella cells as well as trichome defects (smaller and reduced number of branches).
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Genomic context

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See MYB5 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
2
Sequence:
Chromosome: 3; NC_003074.8 (4419960..4421751)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene mitogen-activated protein kinase kinase kinase 7 Neighboring gene ncRNA Neighboring gene Ubiquitin-conjugating enzyme family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. MYB-bHLH-TTG1 in a Multi-tiered Pathway Regulates Arabidopsis Seed Coat Mucilage Biosynthesis Genes Including PECTIN METHYLESTERASE INHIBITOR14 Required for Homogalacturonan Demethylesterification. Allen PJ, et al. Plant Cell Physiol, 2023 Aug 17. PMID 37354456, Free PMC Article
  2. The Arabidopsis MYB5 transcription factor regulates mucilage synthesis, seed coat development, and trichome morphogenesis. Li SF, et al. Plant Cell, 2009 Jan. PMID 19136646, Free PMC Article
  3. A novel myb-related gene from Arabidopsis thaliana. Li SF, et al. FEBS Lett, 1996 Jan 29. PMID 8635574
  4. The Seed Development Factors TT2 and MYB5 Regulate Heat Stress Response in Arabidopsis. Jacob P, et al. Genes (Basel), 2021 May 15. PMID 34063415, Free PMC Article
  5. TTG1 complex MYBs, MYB5 and TT2, control outer seed coat differentiation. Gonzalez A, et al. Dev Biol, 2009 Jan 15. PMID 18992236

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The Seed Development Factors TT2 and MYB5 Regulate Heat Stress Response in Arabidopsis.
    Title: The Seed Development Factors TT2 and MYB5 Regulate Heat Stress Response in Arabidopsis.
  2. This publication identifies AtMYB5 and TT2, as partially redundant in regulating the outer seed coat developmental process with MYB5 having the major role. MYB5 and TT2 are shown to be expressed in this outer seed coat domain. [MYB5]
    Title: TTG1 complex MYBs, MYB5 and TT2, control outer seed coat differentiation.
  3. MYB5 gene is expressed in trichomes and seeds, and regulates trichome extension and branching.
    Title: The Arabidopsis MYB5 transcription factor regulates mucilage synthesis, seed coat development, and trichome morphogenesis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_112200.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables DNA binding TAS
Traceable Author Statement
more info
 PubMed 
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within mucilage biosynthetic process involved in seed coat development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of gene expression IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within seed coat development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within seed germination NAS
Non-traceable Author Statement
more info
  
acts_upstream_of_or_within trichome differentiation NAS
Non-traceable Author Statement
more info
  
acts_upstream_of_or_within trichome morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
myb domain protein 5
NP_187963.1
  • myb domain protein 5 (MYB5); CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Homeodomain-like (InterPro:IPR009057), Myb, DNA-binding (InterPro:IPR014778), HTH transcriptional regulator, Myb-type, DNA-binding (InterPro:IPR017930), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: myb domain protein 17 (TAIR:AT3G61250.1); Has 8972 Blast hits to 8275 proteins in 512 species: Archae - 0; Bacteria - 0; Metazoa - 834; Fungi - 461; Plants - 5987; Viruses - 3; Other Eukaryotes - 1687 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    4419960..4421751
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_112200.3 → NP_187963.1  myb domain protein 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_187963.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q38850
    UniProtKB/TrEMBL
    A0A178VAR4, A0A5S9XC04
    Conserved Domains (1) summary
    PLN03212
    Location:1 → 249
    PLN03212; Transcription repressor MYB5; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q38850.1

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