FAD7 fatty acid desaturase 7 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: FAD7
Official Full Name: fatty acid desaturase 7
Primary source: TAIR:AT3G11170
Locus tag: AT3G11170
See related: Araport:AT3G11170
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtFAD7; CHLOROPLAST PRECURSOR; FADD; fatty acid desaturase 7; FATTY ACID DESATURASE D; OMEGA-3 FATTY ACID DESATURASE
Summary: Chloroplastic enzyme responsible for the synthesis of 16:3 and 18:3 fatty acids from galactolipids, sulpholipids and phosphatidylglycerol. Uses ferredoxin as electron donor. Gene expression is induced by wounding in shoot and root. The wound-response in shoot is independent of jasmonic acid mediated pathway whereas the root response is mediated by jasmonic acid.
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Genomic context

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See FAD7 in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 8

Sequence:: Chromosome: 3; NC_003074.8 (3499537..3502452)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

the codon preference of FAD7 is influenced by genetic relationships
Title: Analysis of synonymous codon usage in FAD7 genes from different plant species.
FAD7 catalyses the production of jasmonic acid, andis induced locally by wounding. RNA polymerase II C-terminal domain phosphatases are negative regulators of FAD7 expression.
Title: CTD phosphatases in the attenuation of wound-induced transcription of jasmonic acid biosynthetic genes in Arabidopsis.
When young, cold-induced tobacco seedlings were exposed to low-temperature (0.5, 2 or 3.5 degrees C) for up to 44 days, survival within independent cor15a-FAD7 transgenic lines (40.2-96%) was far superior to the wild type (6.7-10.2%).
Title: Enhanced cold tolerance in transgenic tobacco expressing a chloroplast omega-3 fatty acid desaturase gene under the control of a cold-inducible promoter.
These results suggest that the ozone-induced expression of FAD7 gene requires SA, but not ethylene, JA, NPR1 and SID2.
Title: Ozone-induced expression of the Arabidopsis FAD7 gene requires salicylic acid, but not NPR1 and SID2.

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_111953.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables omega-3 fatty acid desaturase activity	IGI Inferred from Genetic Interaction more info	PubMed
enables sn-2 acyl-lipid omega-3 desaturase (ferredoxin) activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within fatty acid biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to cold	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in unsaturated fatty acid biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in chloroplast	HDA more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in chloroplast	ISS Inferred from Sequence or Structural Similarity more info	PubMed
located_in chloroplast	NAS Non-traceable Author Statement more info	PubMed
located_in chloroplast envelope	HDA more info	PubMed
located_in cytosol	HDA more info	PubMed
located_in plastid membrane	TAS Traceable Author Statement more info	PubMed

General protein information

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Preferred Names: fatty acid desaturase 7

NP_187727.1

fatty acid desaturase 7 (FAD7); FUNCTIONS IN: omega-3 fatty acid desaturase activity; INVOLVED IN: response to cold, response to wounding, fatty acid biosynthetic process, jasmonic acid mediated signaling pathway; LOCATED IN: plastid membrane, chloroplast, chloroplast envelope; EXPRESSED IN: male gametophyte, guard cell, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF3474 (InterPro:IPR021863), Fatty acid desaturase, type 1 (InterPro:IPR005804); BEST Arabidopsis thaliana protein match is: fatty acid desaturase 8 (TAIR:AT5G05580.1); Has 2938 Blast hits to 2935 proteins in 698 species: Archae - 0; Bacteria - 1234; Metazoa - 17; Fungi - 265; Plants - 926; Viruses - 0; Other Eukaryotes - 496 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

3499537..3502452

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_111953.3 → NP_187727.1 fatty acid desaturase 7 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_187727.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P46310

UniProtKB/TrEMBL

A0A178VH06, A0A654F5Z9, Q94EW6

Conserved Domains (1) summary

PLN02498
Location:1 → 442

PLN02498; omega-3 fatty acid desaturase