SGT UDP-Glycosyltransferase superfamily protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: SGT
Official Full Name: UDP-Glycosyltransferase superfamily protein
Primary source: TAIR:AT3G07020
Locus tag: AT3G07020
See related: Araport:AT3G07020
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: sterol glucosyltransferase; UDP-glucosyl transferase 80A2; UGT80A2
Summary: encodes a 3beta-hydroxy sterol UDP-glucosyltransferase. ugt80a2 mutant plants have reduced steryl glycoside and acyl steryl glycoside levels and reduced seed size. ugt80a2/b1 double mutants have normal levels of celluose and normal cold stress tolerance.
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Genomic context

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See SGT in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 15

Sequence:: Chromosome: 3; NC_003074.8 (2217622..2221956, complement)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Both UGT80A2 and UGT80B1, but not UGT713B1 were shown to be coordinately down-regulated during seed imbibition when SG levels decline, consistent with similar functions as UGT80 enzymes.
Title: Functional diversification of two UGT80 enzymes required for steryl glucoside synthesis in Arabidopsis.
Arabidopsis lines having mutations in UGT80A2, UGT80B1, or both UGT80A2 and UGT80B1 were identified and characterized.
Title: Mutations in UDP-Glucose:sterol glucosyltransferase in Arabidopsis cause transparent testa phenotype and suberization defect in seeds.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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NM_001337686.1

Supported by ESTs:

NM_111582.3

Supported by ESTs:

NM_180198.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables glycosyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables sterol 3-beta-glucosyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables sterol 3-beta-glucosyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
NOT involved_in cellulose biosynthetic process	IGI Inferred from Genetic Interaction more info	PubMed
NOT involved_in cold acclimation	IGI Inferred from Genetic Interaction more info	PubMed
involved_in lipid glycosylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within seed development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within sterol metabolic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	HDA more info	PubMed
located_in nucleus	ISM Inferred from Sequence Model more info
located_in plasma membrane	HDA more info	PubMed

General protein information

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Preferred Names: UDP-Glycosyltransferase superfamily protein

NP_566297.2

UDP-Glycosyltransferase superfamily protein; FUNCTIONS IN: transferase activity, transferring glycosyl groups; INVOLVED IN: lipid glycosylation, carbohydrate metabolic process, metabolic process; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Glycosyl transferase, family 28 (InterPro:IPR004276), UDP-glucuronosyl/UDP-glucosyltransferase (InterPro:IPR002213); BEST Arabidopsis thaliana protein match is: UDP-Glycosyltransferase superfamily protein (TAIR:AT1G43620.3); Has 2464 Blast hits to 2426 proteins in 636 species: Archae - 0; Bacteria - 1528; Metazoa - 298; Fungi - 386; Plants - 152; Viruses - 3; Other Eukaryotes - 97 (source: NCBI BLink).

NP_850529.1

UDP-Glycosyltransferase superfamily protein; FUNCTIONS IN: transferase activity, transferring glycosyl groups; INVOLVED IN: lipid glycosylation, carbohydrate metabolic process, metabolic process; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Glycosyl transferase, family 28 (InterPro:IPR004276), UDP-glucuronosyl/UDP-glucosyltransferase (InterPro:IPR002213); BEST Arabidopsis thaliana protein match is: UDP-Glycosyltransferase superfamily protein (TAIR:AT1G43620.3); Has 2447 Blast hits to 2409 proteins in 631 species: Archae - 0; Bacteria - 1513; Metazoa - 298; Fungi - 386; Plants - 150; Viruses - 3; Other Eukaryotes - 97 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

2217622..2221956 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_180198.3 → NP_850529.1 UDP-Glycosyltransferase superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_850529.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A7G2EMW6, W8PUV4

Conserved Domains (2) summary

cd03784
Location:193 → 609

GT1_Gtf_like; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the ...

COG1819
Location:192 → 609

YjiC; UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]
NM_111582.3 → NP_566297.2 UDP-Glycosyltransferase superfamily protein [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_566297.2

Status: REVIEWED

UniProtKB/Swiss-Prot

B9DFL3, O23649, Q93ZJ2, Q9M8Z7

UniProtKB/TrEMBL

A0A178VKP8, A0A5S9X9Y6

Conserved Domains (2) summary

cd03784
Location:193 → 609

GT1_Gtf_like; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the ...

COG1819
Location:192 → 609

YjiC; UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]
NM_001337686.1 → NP_001326118.1 UDP-Glycosyltransferase superfamily protein [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A178VKP8, A0A1I9LNA9, A0A5S9X9Y6