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LACS6 long-chain acyl-CoA synthetase 6 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819767, updated on 18-Sep-2024

Summary

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Official Symbol
LACS6
Official Full Name
long-chain acyl-CoA synthetase 6
Primary source
TAIR:AT3G05970
Locus tag
AT3G05970
See related
Araport:AT3G05970
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATLACS6; F2O10.7; F2O10_7; long-chain acyl-CoA synthetase 6
Summary
encode peroxisomal long-chain acyl-CoA synthetase (LACS) isozymes
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Genomic context

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See LACS6 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
23
Sequence:
Chromosome: 3; NC_003074.8 (1786279..1791887, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene RmlC-like cupins superfamily protein Neighboring gene sugar transporter 6 Neighboring gene Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Two long-chain acyl-CoA synthetases from Arabidopsis thaliana involved in peroxisomal fatty acid beta-oxidation. Fulda M, et al. Plant J, 2002 Oct. PMID 12366803
  2. Intrinsic acyl-CoA thioesterase activity of a peroxisomal ATP binding cassette transporter is required for transport and metabolism of fatty acids. De Marcos Lousa C, et al. Proc Natl Acad Sci U S A, 2013 Jan 22. PMID 23288899, Free PMC Article
  3. AtLACS7 interacts with the TPR domains of the PTS1 receptor PEX5. Bonsegna S, et al. Arch Biochem Biophys, 2005 Nov 15. PMID 16256065
  4. Arabidopsis contains nine long-chain acyl-coenzyme a synthetase genes that participate in fatty acid and glycerolipid metabolism. Shockey JM, et al. Plant Physiol, 2002 Aug. PMID 12177484, Free PMC Article
  5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_111471.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables long-chain fatty acid-CoA ligase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables long-chain fatty acid-CoA ligase activity TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid metabolic process TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within long-chain fatty acid metabolic process TAS
Traceable Author Statement
more info
  
involved_in response to ozone IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in cytosol HDA PubMed 
located_in peroxisome IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
long-chain acyl-CoA synthetase 6
NP_566265.1
  • long-chain acyl-CoA synthetase 6 (LACS6); FUNCTIONS IN: long-chain fatty acid-CoA ligase activity; INVOLVED IN: long-chain fatty acid metabolic process; LOCATED IN: membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: AMP-binding, conserved site (InterPro:IPR020845), AMP-dependent synthetase/ligase (InterPro:IPR000873); BEST Arabidopsis thaliana protein match is: long-chain acyl-CoA synthetase 7 (TAIR:AT5G27600.1); Has 54528 Blast hits to 52136 proteins in 3333 species: Archae - 925; Bacteria - 35165; Metazoa - 2570; Fungi - 2253; Plants - 2087; Viruses - 1; Other Eukaryotes - 11527 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    1786279..1791887 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_111471.3 → NP_566265.1  long-chain acyl-CoA synthetase 6 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_566265.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LKS6, Q8LPS1, Q9C5U7, Q9SFG1
    UniProtKB/TrEMBL
    A0A178VG06, A0A5S9X9I0
    Conserved Domains (1) summary
    PLN02736
    Location:41 → 691
    PLN02736; long-chain acyl-CoA synthetase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8LPS1.1

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