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3-beta hydroxysteroid dehydrogenase/isomerase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 818943, updated on 14-Nov-2024

Summary

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Official Full Name
3-beta hydroxysteroid dehydrogenase/isomerase family protein
Primary source
TAIR:AT2G43420
Locus tag
AT2G43420
See related
Araport:AT2G43420
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
T1O24.16
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Genomic context

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Location:
chromosome: 2
Exon count:
12
Sequence:
Chromosome: 2; NC_003071.7 (18031268..18035182, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene electron-transfer flavoprotein:ubiquinone oxidoreductase Neighboring gene ncRNA Neighboring gene RNA binding protein Neighboring gene glyoxalase 2-1 Neighboring gene F-box and associated interaction domains-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The odd one out: Arabidopsis reticulon 20 does not bend ER membranes but has a role in lipid regulation. Kriechbaumer V, et al. Sci Rep, 2018 Feb 2. PMID 29396477, Free PMC Article
  2. Arabidopsis plasmodesmal proteome. Fernandez-Calvino L, et al. PLoS One, 2011 Apr 20. PMID 21533090, Free PMC Article
  3. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
  4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_129903.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables 3-beta-hydroxy-delta5-steroid dehydrogenase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
  
enables 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) [NAD(+)] activity IEA
Inferred from Electronic Annotation
more info
  
enables C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasmodesma HDA PubMed 

General protein information

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Preferred Names
3-beta hydroxysteroid dehydrogenase/isomerase family protein
NP_565998.1
  • 3-beta hydroxysteroid dehydrogenase/isomerase family protein; FUNCTIONS IN: binding, 3-beta-hydroxy-delta5-steroid dehydrogenase activity, catalytic activity; INVOLVED IN: steroid biosynthetic process, metabolic process; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Reticulon (InterPro:IPR003388), 3-beta hydroxysteroid dehydrogenase/isomerase (InterPro:IPR002225), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2 (TAIR:AT2G26260.1); Has 10307 Blast hits to 10296 proteins in 2122 species: Archae - 301; Bacteria - 6803; Metazoa - 545; Fungi - 280; Plants - 752; Viruses - 81; Other Eukaryotes - 1545 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    18031268..18035182 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_129903.3 → NP_565998.1  3-beta hydroxysteroid dehydrogenase/isomerase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_565998.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A9X4U2, O22856, Q94AR9
    UniProtKB/TrEMBL
    A0A178W0W0, A0A5S9X6X5
    Conserved Domains (2) summary
    cd09813
    Location:14 → 354
    3b-HSD-NSDHL-like_SDR_e; human NSDHL (NAD(P)H steroid dehydrogenase-like protein)-like, extended (e) SDRs
    pfam02453
    Location:379 → 537
    Reticulon
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A9X4U2.2

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