LTP2 lipid transfer protein 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: LTP2
Official Full Name: lipid transfer protein 2
Primary source: TAIR:AT2G38530
Locus tag: AT2G38530
See related: Araport:AT2G38530
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: cdf3; cell growth defect factor-3; LIPID TRANSFER PROTEIN; lipid transfer protein 2; LP2; T6A23.27; T6A23_27
Summary: Involved in lipid transfer between membranes. Belongs to a family of Lipid transfer proteins. Sequence similarity to other plant/Arabidopsis LPT genes but highest similarity to LPT1. Stress and pathogen-inducible motifs found in the upstream region. Expressed in flower, leaves and siliques but absent in roots. Predicted to be a member of PR-14 pathogenesis-related protein family with the following members: At2g38540/LTP1, At2g38530/LTP2, At5g59320/LTP3, At5g59310/LTP4, At3g51600/LTP5, At3g08770/LTP6, At2g15050/LTP7, At2g18370/LTP8, At2g15325/LTP9, At5g01870/LTP10, At4g33355/LTP11, At3g51590/LTP12, At5g44265/LTP13, At5g62065/LTP14, At4g08530/LTP15.
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Genomic context

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See LTP2 in Genome Data Viewer

Location:: chromosome: 2

Exon count:: 2

Sequence:: Chromosome: 2; NC_003071.7 (16128176..16129399)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

LTP2 hypomorphs show genotype-by-environment interaction in early seedling traits in Arabidopsis thaliana.
Title: LTP2 hypomorphs show genotype-by-environment interaction in early seedling traits in Arabidopsis thaliana.
bHLH transcription factors LP1 and LP2 regulate longitudinal cell elongation.
Title: bHLH transcription factors LP1 and LP2 regulate longitudinal cell elongation.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_129410.5

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cutin biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within cutin-based cuticle development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within phospholipid transfer to membrane	NAS Non-traceable Author Statement more info	PubMed
acts_upstream_of_or_within plant epidermal cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within programmed cell death	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within response to water deprivation	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	HDA more info	PubMed
located_in chloroplast	IDA Inferred from Direct Assay more info	PubMed
located_in endosome	HDA more info	PubMed
located_in extracellular region	ISM Inferred from Sequence Model more info
located_in plant-type cell wall	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	HDA more info	PubMed
located_in trans-Golgi network	HDA more info	PubMed

General protein information

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Preferred Names: lipid transfer protein 2

NP_181387.1

lipid transfer protein 2 (LTP2); FUNCTIONS IN: lipid binding; INVOLVED IN: programmed cell death, phospholipid transfer to membrane; LOCATED IN: plasma membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Bifunctional inhibitor/plant lipid transfer protein/seed storage (InterPro:IPR016140), Plant lipid transfer protein/seed storage/trypsin-alpha amylase inhibitor (InterPro:IPR003612), Plant lipid transfer protein/Par allergen (InterPro:IPR000528), Plant lipid transfer protein/hydrophobic protein, helical domain (InterPro:IPR013770); BEST Arabidopsis thaliana protein match is: lipid transfer protein 1 (TAIR:AT2G38540.1); Has 1099 Blast hits to 1099 proteins in 127 species: Archae - 0; Bacteria - 0; Metazoa - 2; Fungi - 0; Plants - 1096; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003071.7 Reference assembly

Range

16128176..16129399

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_129410.5 → NP_181387.1 lipid transfer protein 2 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_181387.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q3C1C6, Q41935, Q43277, Q43280, Q9S7I3

UniProtKB/TrEMBL

A0A178W063, A0A5S9X562, A0A654FAK5

Conserved Domains (1) summary

cd01960
Location:28 → 115

nsLTP1; Non-specific lipid-transfer protein type 1 (nsLTP1) subfamily; Plant nsLTPs are small, soluble proteins that facilitate the transfer of fatty acids, phospholipids, glycolipids, and steroids between membranes. In addition to lipid transport and assembly, ...