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SETH1 phosphatidylinositolglycan synthase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 818062, updated on 18-Sep-2024

Summary

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Official Symbol
SETH1
Official Full Name
phosphatidylinositolglycan synthase family protein
Primary source
TAIR:AT2G34980
Locus tag
AT2G34980
See related
Araport:AT2G34980
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F19I3.21; F19I3_21
Summary
Encodes a putative phosphatidylinositol-glycan synthase subunit C gene. It is involved in the first step of the glycosylphosphatidylinositol (GPI) biosynthetic pathway.
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Genomic context

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See SETH1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
1
Sequence:
Chromosome: 2; NC_003071.7 (14748877..14749878)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene cationic amino acid transporter 5 Neighboring gene Trimeric LpxA-like enzyme Neighboring gene tRNA-Thr Neighboring gene RING/U-box superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. SETH1 and SETH2, two components of the glycosylphosphatidylinositol anchor biosynthetic pathway, are required for pollen germination and tube growth in Arabidopsis. Lalanne E, et al. Plant Cell, 2004 Jan. PMID 14671020, Free PMC Article
  2. A user-friendly platform for yeast two-hybrid library screening using next generation sequencing. Erffelinck ML, et al. PLoS One, 2018. PMID 30576311, Free PMC Article
  3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_129050.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
contributes_to phosphatidylinositol N-acetylglucosaminyltransferase activity TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within GPI anchor biosynthetic process TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within pollen germination IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within pollen tube growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex TAS
Traceable Author Statement
more info
 PubMed 
located_in membrane TAS
Traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositolglycan synthase family protein
NP_181043.1
  • SETH1; CONTAINS InterPro DOMAIN/s: Phosphatidylinositol N-acetylglucosaminyltransferase (InterPro:IPR009450); Has 335 Blast hits to 331 proteins in 171 species: Archae - 0; Bacteria - 0; Metazoa - 120; Fungi - 117; Plants - 38; Viruses - 0; Other Eukaryotes - 60 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    14748877..14749878
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_129050.2 → NP_181043.1  phosphatidylinositolglycan synthase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_181043.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O64761
    UniProtKB/TrEMBL
    A0A178VQ18, A0A5S9X4J5
    Conserved Domains (1) summary
    pfam06432
    Location:15 → 293
    GPI2; Phosphatidylinositol N-acetylglucosaminyltransferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O64761.1

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