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Rpl13 ribosomal protein L13 [ Rattus norvegicus (Norway rat) ]

Gene ID: 81765, updated on 2-Nov-2024

Summary

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Official Symbol
Rpl13provided by RGD
Official Full Name
ribosomal protein L13provided by RGD
Primary source
RGD:621179
See related
EnsemblRapid:ENSRNOG00000015335 AllianceGenome:RGD:621179
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Involved in liver regeneration. Part of cytosolic large ribosomal subunit. Orthologous to human RPL13 (ribosomal protein L13). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Spleen (RPKM 4845.8), Thymus (RPKM 4489.8) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Rpl13 in Genome Data Viewer
Location:
19q12
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (68062442..68065065)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (51153990..51156541)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (55917489..55920040)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102551789 Neighboring gene ribosomal protein S13, pseudogene 1 Neighboring gene SPG7 matrix AAA peptidase subunit, paraplegin Neighboring gene small nucleolar RNA MBII-202 Neighboring gene copine 7 Neighboring gene sulfotransferase family 5A, member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. RPL13 Variants Cause Spondyloepimetaphyseal Dysplasia with Severe Short Stature. Le Caignec C, et al. Am J Hum Genet, 2019 Nov 7. PMID 31630789, Free PMC Article
  2. The primary structure of rat ribosomal protein L13. Olvera J, et al. Biochem Biophys Res Commun, 1994 May 30. PMID 8198561
  3. Coordinate regulation of ribosomal protein mRNA level in regenerating rat liver. Study with the corresponding mouse cloned cDNAs. Faliks D, et al. Nucleic Acids Res, 1982 Feb 11. PMID 6121318, Free PMC Article
  4. Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse. Yu C, et al. Cell Res, 2016 Mar. PMID 26902285, Free PMC Article
  5. Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing. Odintsova TI, et al. J Protein Chem, 2003 Apr. PMID 12962325

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
enables structural constituent of ribosome NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of blastocyst development ISO
Inferred from Sequence Orthology
more info
  
involved_in bone development ISO
Inferred from Sequence Orthology
more info
  
involved_in liver regeneration IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
involved_in translation NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of cytosolic large ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
  
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein eL13
Names
60S ribosomal protein L13
XP_063134380.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031101.2 → NP_112363.2  large ribosomal subunit protein eL13

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000019
    UniProtKB/Swiss-Prot
    P41123
    UniProtKB/TrEMBL
    A6IZV2
    Related
    ENSRNOP00000020635.3, ENSRNOT00000020635.8

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    68062442..68065065
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063278310.1 → XP_063134380.1  large ribosomal subunit protein eL13 isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P41123.2 GenPept UniProtKB/Swiss-Prot:P41123

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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