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FUS12 proteasome family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817241, updated on 18-Sep-2024

Summary

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Official Symbol
FUS12
Official Full Name
proteasome family protein
Primary source
TAIR:AT2G26990
Locus tag
AT2G26990
See related
Araport:AT2G26990
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATCSN2; CONSTITUTIVE PHOTOMORPHOGENIC 12; COP12; CSN2; FUSCA 12; T20P8.4; T20P8_4
Summary
Represses photomorphogenesis and induces skotomorphogenesis in the dark.
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Genomic context

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See FUS12 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
10
Sequence:
Chromosome: 2; NC_003071.7 (11519388..11522616, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Ctr copper transporter family Neighboring gene CBL-interacting protein kinase 3 Neighboring gene cytochrome P450, family 705, subfamily A, polypeptide 8 Neighboring gene cytochrome P450, family 705, subfamily A, polypeptide 9

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. CSN1 N-terminal-dependent activity is required for Arabidopsis development but not for Rub1/Nedd8 deconjugation of cullins: a structure-function study of CSN1 subunit of COP9 signalosome. Wang X, et al. Mol Biol Cell, 2002 Feb. PMID 11854419, Free PMC Article
  2. Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIRI in mediating auxin response. Schwechheimer C, et al. Science, 2001 May 18. PMID 11337587
  3. SMALL ACIDIC PROTEIN1 acts with RUB modification components, the COP9 signalosome, and AXR1 to regulate growth and development of Arabidopsis. Nakasone A, et al. Plant Physiol, 2012 Sep. PMID 22576848, Free PMC Article
  4. The Arabidopsis CSN5A and CSN5B subunits are present in distinct COP9 signalosome complexes, and mutations in their JAMM domains exhibit differential dominant negative effects on development. Gusmaroli G, et al. Plant Cell, 2004 Nov. PMID 15486099, Free PMC Article
  5. The COP9 signalosome: from light signaling to general developmental regulation and back. Karniol B, et al. Curr Opin Plant Biol, 2000 Oct. PMID 11019806

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_128257.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within photomorphogenesis TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within protein catabolic process TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within protein deneddylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of COP9 signalosome TAS
Traceable Author Statement
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  
located_in nucleus TAS
Traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
proteasome family protein
NP_565632.1
  • FUSCA 12 (FUS12); INVOLVED IN: cullin deneddylation, photomorphogenesis, protein catabolic process; LOCATED IN: signalosome, nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Proteasome component (PCI) domain (InterPro:IPR000717), PCI/PINT associated module (InterPro:IPR013143); BEST Arabidopsis thaliana protein match is: non-ATPase subunit 9 (TAIR:AT1G29150.1); Has 881 Blast hits to 877 proteins in 239 species: Archae - 2; Bacteria - 9; Metazoa - 323; Fungi - 235; Plants - 190; Viruses - 0; Other Eukaryotes - 122 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    11519388..11522616 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_128257.4 → NP_565632.1  proteasome family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_565632.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8W207, Q94A24, Q9ZVD8
    UniProtKB/TrEMBL
    A0A178VSH3, A0A5S9X1R9
    Conserved Domains (2) summary
    COG5159
    Location:65 → 406
    RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
    pfam01399
    Location:305 → 405
    PCI; PCI domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8W207.1

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