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APL4 Glucose-1-phosphate adenylyltransferase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 816697, updated on 18-Sep-2024

Summary

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Official Symbol
APL4
Official Full Name
Glucose-1-phosphate adenylyltransferase family protein
Primary source
TAIR:AT2G21590
Locus tag
AT2G21590
See related
Araport:AT2G21590
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F2G1.14; F2G1_14
Summary
Encodes the large subunit of ADP-glucose pyrophosphorylase, the enzyme which catalyzes the first and limiting step in starch biosynthesis. The large subunit plays a regulatory role whereas the small subunit (ApS) is the catalytic isoform. Four isoforms of the large subunit (ApL1-4) have been described.
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Genomic context

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See APL4 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
16
Sequence:
Chromosome: 2; NC_003071.7 (9238296..9242481)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene Ribosomal protein S25 family protein Neighboring gene uncharacterized protein Neighboring gene endoplasmatic reticulum retrieval protein 1B Neighboring gene pectinesterase 11

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The different large subunit isoforms of Arabidopsis thaliana ADP-glucose pyrophosphorylase confer distinct kinetic and regulatory properties to the heterotetrameric enzyme. Crevillén P, et al. J Biol Chem, 2003 Aug 1. PMID 12748181
  2. Two Arabidopsis ADP-glucose pyrophosphorylase large subunits (APL1 and APL2) are catalytic. Ventriglia T, et al. Plant Physiol, 2008 Sep. PMID 18614708, Free PMC Article
  3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
  4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001036314.2
NM_001335766.1
NM_001335767.1
NM_001335768.1
NM_001335769.1
NM_127730.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
contributes_to glucose-1-phosphate adenylyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables glucose-1-phosphate adenylyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycogen biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in starch biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within starch biosynthetic process TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
part_of glucose-1-phosphate adenylyltransferase complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
Glucose-1-phosphate adenylyltransferase family protein
NP_001031391.1
  • APL4; CONTAINS InterPro DOMAIN/s: ADP-glucose pyrophosphorylase, conserved site (InterPro:IPR005836), Glucose-1-phosphate adenylyltransferase (InterPro:IPR011831), Nucleotidyl transferase (InterPro:IPR005835); BEST Arabidopsis thaliana protein match is: Glucose-1-phosphate adenylyltransferase family protein (TAIR:AT4G39210.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
NP_179753.1
  • APL4; CONTAINS InterPro DOMAIN/s: Glucose-1-phosphate adenylyltransferase (InterPro:IPR011831), ADP-glucose pyrophosphorylase, conserved site (InterPro:IPR005836), Nucleotidyl transferase (InterPro:IPR005835); BEST Arabidopsis thaliana protein match is: Glucose-1-phosphate adenylyltransferase family protein (TAIR:AT4G39210.1); Has 8265 Blast hits to 8149 proteins in 1719 species: Archae - 344; Bacteria - 5333; Metazoa - 20; Fungi - 9; Plants - 1699; Viruses - 0; Other Eukaryotes - 860 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    9238296..9242481
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001335765.1 → NP_001324982.1  Glucose-1-phosphate adenylyltransferase family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SIK1
    UniProtKB/TrEMBL
    A0A178VYA8, A0A384KNK6, B9DGF8
    Conserved Domains (1) summary
    PLN02241
    Location:88 → 523
    PLN02241; glucose-1-phosphate adenylyltransferase

  2. NM_127730.5 → NP_179753.1  Glucose-1-phosphate adenylyltransferase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_179753.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SIK1
    UniProtKB/TrEMBL
    A0A178VYA8, A0A384KNK6, B9DGF8
    Conserved Domains (1) summary
    PLN02241
    Location:88 → 523
    PLN02241; glucose-1-phosphate adenylyltransferase

  3. NM_001335766.1 → NP_001324978.1  Glucose-1-phosphate adenylyltransferase family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SIK1
    UniProtKB/TrEMBL
    A0A178VYA8, A0A384KNK6, B9DGF8
    Conserved Domains (1) summary
    PLN02241
    Location:88 → 523
    PLN02241; glucose-1-phosphate adenylyltransferase

  4. NM_001036314.2 → NP_001031391.1  Glucose-1-phosphate adenylyltransferase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001031391.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SIK1
    UniProtKB/TrEMBL
    A0A178VYA8, A0A384KNK6, B9DGF8
    Conserved Domains (1) summary
    PLN02241
    Location:88 → 523
    PLN02241; glucose-1-phosphate adenylyltransferase

  5. NM_001335767.1 → NP_001324979.1  Glucose-1-phosphate adenylyltransferase family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SIK1
    UniProtKB/TrEMBL
    A0A178VYA8, A0A384KNK6, B9DGF8
    Conserved Domains (1) summary
    PLN02241
    Location:88 → 523
    PLN02241; glucose-1-phosphate adenylyltransferase

  6. NM_001335768.1 → NP_001324980.1  Glucose-1-phosphate adenylyltransferase family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SIK1
    UniProtKB/TrEMBL
    A0A178VYA8, A0A384KNK6, B9DGF8
    Conserved Domains (1) summary
    PLN02241
    Location:88 → 523
    PLN02241; glucose-1-phosphate adenylyltransferase

  7. NM_001335769.1 → NP_001324981.1  Glucose-1-phosphate adenylyltransferase family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SIK1
    UniProtKB/TrEMBL
    A0A178VYA8, A0A384KNK6, B9DGF8
    Conserved Domains (1) summary
    PLN02241
    Location:88 → 523
    PLN02241; glucose-1-phosphate adenylyltransferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SIK1.1

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