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LAX2 uncharacterized protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 816640, updated on 18-Sep-2024

Summary

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Official Symbol
LAX2
Official Full Name
uncharacterized protein
Primary source
TAIR:AT2G21050
Locus tag
AT2G21050
See related
Araport:AT2G21050
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F26H11.19; F26H11_19; like AUXIN RESISTANT 2
Summary
Encodes LAX2 (LIKE AUXIN RESISTANT), a member of the AUX1 LAX family of auxin influx carriers. Required for the establishment of embryonic root cell organization.
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Genomic context

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See LAX2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
6
Sequence:
Chromosome: 2; NC_003071.7 (9034056..9036636)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Calcium-dependent lipid-binding (CaLB domain) family protein Neighboring gene Rhodanese/Cell cycle control phosphatase superfamily protein Neighboring gene glycine-rich protein 2B Neighboring gene methyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A role for LAX2 in regulating xylem development and lateral-vein symmetry in the leaf. Moreno-Piovano GS, et al. Ann Bot, 2017 Oct 17. PMID 28981582, Free PMC Article
  2. Auxin influx importers modulate serration along the leaf margin. Kasprzewska A, et al. Plant J, 2015 Aug. PMID 26111009, Free PMC Article
  3. AUX/LAX genes encode a family of auxin influx transporters that perform distinct functions during Arabidopsis development. Péret B, et al. Plant Cell, 2012 Jul. PMID 22773749, Free PMC Article
  4. Auxin influx carriers control vascular patterning and xylem differentiation in Arabidopsis thaliana. Fàbregas N, et al. PLoS Genet, 2015 Apr. PMID 25922946, Free PMC Article
  5. The AUX1 LAX family of auxin influx carriers is required for the establishment of embryonic root cell organization in Arabidopsis thaliana. Ugartechea-Chirino Y, et al. Ann Bot, 2010 Feb. PMID 19952011, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. role in regulating xylem development and lateral-vein symmetry in the leaf
    Title: A role for LAX2 in regulating xylem development and lateral-vein symmetry in the leaf.
  2. Data report that three of these genes (AUX1, LAX1 and LAX2) show specific and dynamic patterns of expression during early leaf development
    Title: Auxin influx importers modulate serration along the leaf margin.
  3. we observed fewer and more spaced vascular bundles in quadruple mutants plants of the auxin influx carriers aux1lax1lax2lax3
    Title: Auxin influx carriers control vascular patterning and xylem differentiation in Arabidopsis thaliana.
  4. LAX2 regulates vascular patterning in cotyledons.
    Title: AUX/LAX genes encode a family of auxin influx transporters that perform distinct functions during Arabidopsis development.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_127675.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables amino acid transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cotyledon vascular tissue pattern formation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to nematode HEP PubMed 
acts_upstream_of_or_within root cap development IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within somatic embryogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
uncharacterized protein
NP_179701.1
  • like AUXIN RESISTANT 2 (LAX2); CONTAINS InterPro DOMAIN/s: Amino acid transporter, transmembrane (InterPro:IPR013057); BEST Arabidopsis thaliana protein match is: like AUX1 3 (TAIR:AT1G77690.1); Has 1017 Blast hits to 1012 proteins in 134 species: Archae - 0; Bacteria - 2; Metazoa - 94; Fungi - 224; Plants - 668; Viruses - 0; Other Eukaryotes - 29 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    9034056..9036636
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_127675.3 → NP_179701.1  uncharacterized protein AT2G21050 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_179701.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9S836
    UniProtKB/TrEMBL
    A0A178VQ86, A0A5S9X065
    Conserved Domains (1) summary
    PLN03074
    Location:2 → 461
    PLN03074; auxin influx permease; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9S836.1

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