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ASE1 GLN phosphoribosyl pyrophosphate amidotransferase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 816156, updated on 18-Sep-2024

Summary

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Official Symbol
ASE1
Official Full Name
GLN phosphoribosyl pyrophosphate amidotransferase 1
Primary source
TAIR:AT2G16570
Locus tag
AT2G16570
See related
Araport:AT2G16570
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATASE; ATASE1; GLN phosphoribosyl pyrophosphate amidotransferase 1
Summary
Amidophosphoribosyltransferase (ATase: EC 2.4.2.14) is a key enzyme in the pathway of purine nucleotide biosynthesis
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Genomic context

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See ASE1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
1
Sequence:
Chromosome: 2; NC_003071.7 (7180142..7182287, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene pseudo Neighboring gene SAUR-like auxin-responsive protein family Neighboring gene mucin Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Two amidophosphoribosyltransferase genes of Arabidopsis thaliana expressed in different organs. Ito T, et al. Plant Mol Biol, 1994 Oct. PMID 7948903
  2. Characterization of Arabidopsis glutamine phosphoribosyl pyrophosphate amidotransferase-deficient mutants. Hung WF, et al. Plant Physiol, 2004 Jul. PMID 15266056, Free PMC Article
  3. Chemical genetic identification of glutamine phosphoribosylpyrophosphate amidotransferase as the target for a novel bleaching herbicide in Arabidopsis. Walsh TA, et al. Plant Physiol, 2007 Jul. PMID 17616508, Free PMC Article
  4. In-depth temporal transcriptome profiling reveals a crucial developmental switch with roles for RNA processing and organelle metabolism that are essential for germination in Arabidopsis. Narsai R, et al. Plant Physiol, 2011 Nov. PMID 21908688, Free PMC Article
  5. Capturing the phosphorylation and protein interaction landscape of the plant TOR kinase. Van Leene J, et al. Nat Plants, 2019 Mar. PMID 30833711

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables amidophosphoribosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in 'de novo' IMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within purine nucleobase biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast stroma IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plant-type cell wall HDA PubMed 
located_in plastid HDA PubMed 
located_in plastid stroma IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
GLN phosphoribosyl pyrophosphate amidotransferase 1
NP_179247.1
  • GLN phosphoribosyl pyrophosphate amidotransferase 1 (ASE1); FUNCTIONS IN: amidophosphoribosyltransferase activity; INVOLVED IN: purine base biosynthetic process, metabolic process; LOCATED IN: cell wall; EXPRESSED IN: 13 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Glutamine amidotransferase, class-II (InterPro:IPR000583), Phosphoribosyltransferase (InterPro:IPR000836), Amidophosphoribosyl transferase (InterPro:IPR005854), Glutamine amidotransferase, type II (InterPro:IPR017932); BEST Arabidopsis thaliana protein match is: GLN phosphoribosyl pyrophosphate amidotransferase 2 (TAIR:AT4G34740.1); Has 21477 Blast hits to 21465 proteins in 2911 species: Archae - 627; Bacteria - 12302; Metazoa - 410; Fungi - 379; Plants - 300; Viruses - 17; Other Eukaryotes - 7442 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    7180142..7182287 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_127208.2 → NP_179247.1  GLN phosphoribosyl pyrophosphate amidotransferase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_179247.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q38999, Q9SI61
    UniProtKB/TrEMBL
    A0A5S9WYG2, A0A654EYF1
    Conserved Domains (1) summary
    PLN02440
    Location:90 → 566
    PLN02440; amidophosphoribosyltransferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SI61.1

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