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VPS11 vacuolar protein sorting 11 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 815065, updated on 18-Sep-2024

Summary

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Official Symbol
VPS11
Official Full Name
vacuolar protein sorting 11
Primary source
TAIR:AT2G05170
Locus tag
AT2G05170
See related
Araport:AT2G05170
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATVPS11; F5G3.7; F5G3_7; vacuolar protein sorting 11
Summary
Homologous to yeast VPS11. Forms a complex with VCL1 and AtVPS33. Involved in vacuolar biogenesis.
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Genomic context

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See VPS11 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
6
Sequence:
Chromosome: 2; NC_003071.7 (1869853..1873997)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene CCCH-type zinc fingerfamily protein with RNA-binding domain-containing protein Neighboring gene miscRNA Neighboring gene cytochrome P450, family 705, subfamily A, polypeptide 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. AtVps11 is essential for vacuole biogenesis in embryo and participates in pollen tube growth in Arabidopsis. Tan X, et al. Biochem Biophys Res Commun, 2017 Sep 23. PMID 28711500
  2. The AtC-VPS protein complex is localized to the tonoplast and the prevacuolar compartment in arabidopsis. Rojo E, et al. Mol Biol Cell, 2003 Feb. PMID 12589039, Free PMC Article
  3. Distinct sets of tethering complexes, SNARE complexes, and Rab GTPases mediate membrane fusion at the vacuole in Arabidopsis. Takemoto K, et al. Proc Natl Acad Sci U S A, 2018 Mar 6. PMID 29463724, Free PMC Article
  4. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
  5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_126544.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within vacuole organization TAS
Traceable Author Statement
more info
 PubMed 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of CORVET complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of HOPS complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  
located_in plant-type vacuole membrane IDA
Inferred from Direct Assay
more info
 PubMed 
part_of protein-containing complex IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
vacuolar protein sorting 11
NP_027676.1
  • vacuolar protein sorting 11 (VPS11); FUNCTIONS IN: transporter activity, binding, zinc ion binding; INVOLVED IN: vacuole organization; LOCATED IN: plant-type vacuole membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Vacuolar protein sorting-associated protein 11 (InterPro:IPR016528), Zinc finger, RING-type (InterPro:IPR001841), Armadillo-type fold (InterPro:IPR016024); Has 716 Blast hits to 615 proteins in 203 species: Archae - 0; Bacteria - 2; Metazoa - 251; Fungi - 269; Plants - 42; Viruses - 0; Other Eukaryotes - 152 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    1869853..1873997
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_126544.3 → NP_027676.1  vacuolar protein sorting 11 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_027676.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LG85, Q9SJ40
    UniProtKB/TrEMBL
    A0A5S9WX91, A0A654EX07
    Conserved Domains (4) summary
    cd16688
    Location:840 → 880
    RING-H2_Vps11; RING finger, H2 subclass, found in vacuolar protein sorting-associated protein 11 homolog (Vps11) and similar proteins
    pfam00637
    Location:392 → 531
    Clathrin; Region in Clathrin and VPS
    pfam12451
    Location:881 → 923
    VPS11_C; Vacuolar protein sorting protein 11 C terminal
    cl26078
    Location:656 → 747
    Clathrin; Region in Clathrin and VPS
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SJ40.1

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