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CPSF73-II cleavage and polyadenylation specificity factor 73 kDa subunit-II [ Arabidopsis thaliana (thale cress) ]

Gene ID: 814702, updated on 18-Sep-2024

Summary

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Official Symbol
CPSF73-II
Official Full Name
cleavage and polyadenylation specificity factor 73 kDa subunit-II
Primary source
TAIR:AT2G01730
Locus tag
AT2G01730
See related
Araport:AT2G01730
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATCPSF73-II; cleavage and polyadenylation specificity factor 73 kDa subunit-II; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 73 KDA SUBUNIT-II; EDA26; embryo sac development arrest 26; T8O11.10; T8O11_10
Summary
a homolog of cleavage and polyadenylation specificity factor that plays an essential role in the development of female gametophyte and embryo
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Genomic context

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See CPSF73-II in Genome Data Viewer
Location:
chromosome: 2
Exon count:
12
Sequence:
Chromosome: 2; NC_003071.7 (320433..323963)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Chaperone DnaJ-domain superfamily protein Neighboring gene Ribophorin I Neighboring gene RING-finger protein for embryogenesi Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A high-resolution map of Arabidopsis recombinant inbred lines by whole-genome exon array hybridization. Singer T, et al. PLoS Genet, 2006 Sep 15. PMID 17044735, Free PMC Article
  2. Distinctive interactions of the Arabidopsis homolog of the 30 kD subunit of the cleavage and polyadenylation specificity factor (AtCPSF30) with other polyadenylation factor subunits. Rao S, et al. BMC Cell Biol, 2009 Jul 2. PMID 19573236, Free PMC Article
  3. The 73 kD subunit of the cleavage and polyadenylation specificity factor (CPSF) complex affects reproductive development in Arabidopsis. Xu R, et al. Plant Mol Biol, 2006 Jul. PMID 16897494
  4. Unique features of plant cleavage and polyadenylation specificity factor revealed by proteomic studies. Zhao H, et al. Plant Physiol, 2009 Nov. PMID 19748916, Free PMC Article
  5. Arabidopsis mRNA polyadenylation machinery: comprehensive analysis of protein-protein interactions and gene expression profiling. Hunt AG, et al. BMC Genomics, 2008 May 14. PMID 18479511, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Two 73 kD subunits of the AtCPSF complex appear to have special functions during flower development.
    Title: The 73 kD subunit of the cleavage and polyadenylation specificity factor (CPSF) complex affects reproductive development in Arabidopsis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_126234.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within polar nucleus fusion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
cleavage and polyadenylation specificity factor 73 kDa subunit-II
NP_178282.2
  • cleavage and polyadenylation specificity factor 73 kDa subunit-II (CPSF73-II); CONTAINS InterPro DOMAIN/s: RNA-metabolising metallo-beta-lactamase (InterPro:IPR011108), Beta-Casp domain (InterPro:IPR022712), Beta-lactamase-like (InterPro:IPR001279); BEST Arabidopsis thaliana protein match is: cleavage and polyadenylation specificity factor 73-I (TAIR:AT1G61010.3); Has 5072 Blast hits to 5039 proteins in 1435 species: Archae - 491; Bacteria - 2753; Metazoa - 569; Fungi - 259; Plants - 193; Viruses - 0; Other Eukaryotes - 807 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    320433..323963
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001335074.1 → NP_001325256.1  cleavage and polyadenylation specificity factor 73 kDa subunit-II [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B2N2, A0A5S9WWE2

  2. NM_126234.3 → NP_178282.2  cleavage and polyadenylation specificity factor 73 kDa subunit-II [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_178282.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q56XW2, Q8GUU3, Q9ZUA1
    UniProtKB/TrEMBL
    A0A5S9WWE2
    Conserved Domains (4) summary
    smart01027
    Location:244 → 362
    Beta-Casp; Beta-Casp domain
    COG1236
    Location:3 → 446
    YSH1; RNA processing exonuclease, beta-lactamase fold, Cft2 family [Translation, ribosomal structure and biogenesis]
    pfam07521
    Location:378 → 416
    RMMBL; RNA-metabolizing metallo-beta-lactamase
    cd16291
    Location:5 → 203
    INTS11-like_MBL-fold; Integrator complex subunit 11, and related proteins; MBL-fold metallo-hydrolase domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8GUU3.2

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