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FHOD3 formin homology 2 domain containing 3 [ Homo sapiens (human) ]

Gene ID: 80206, updated on 3-Nov-2024

Summary

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Official Symbol
FHOD3provided by HGNC
Official Full Name
formin homology 2 domain containing 3provided by HGNC
Primary source
HGNC:HGNC:26178
See related
Ensembl:ENSG00000134775 MIM:609691; AllianceGenome:HGNC:26178
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CMH28; FHOS2; Formactin2
Summary
The protein encoded by this gene is a member of the diaphanous-related formins (DRF), and contains multiple domains, including GBD (GTPase-binding domain), DID (diaphanous inhibitory domain), FH1 (formin homology 1), FH2 (formin homology 2), and DAD (diaphanous auto-regulatory domain) domains. This protein is thought to play a role in actin filament polymerization in cardiomyocytes. Mutations in this gene have been associated with dilated cardiomyopathy (DCM), characterized by dilation of the ventricular chamber, leading to impairment of systolic pump function and subsequent heart failure. Increased levels of the protein encoded by this gene have been observed in individuals with hypertrophic cardiomyopathy (HCM). Alternative splicing results in multiple transcript variants encoding different isoforms. A muscle-specific isoform has been shown to possess a casein kinase 2 (CK2) phosphorylation site at the C-terminal end of the FH2 domain. Phosphorylation of this site alters its interaction with sequestosome 1 (SQSTM1), and targets this isoform to myofibrils, while other isoforms form cytoplasmic aggregates. [provided by RefSeq, Aug 2015]
Expression
Biased expression in heart (RPKM 23.5), prostate (RPKM 6.1) and 10 other tissues See more
Orthologs
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Genomic context

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See FHOD3 in Genome Data Viewer
Location:
18q12.2
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 18 NC_000018.10 (36297713..36780220)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 18 NC_060942.1 (36489301..36973364)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (33877676..34360183)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene molybdenum cofactor sulfurase Neighboring gene H3K4me1 hESC enhancer GRCh37_chr18:33876522-33877499 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9404 Neighboring gene WDR45-like pseudogene Neighboring gene RNA, U4 small nuclear 3, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13236 Neighboring gene MPRA-validated peak3117 silencer Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:34050630-34051186 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13237 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13238 Neighboring gene MPRA-validated peak3119 silencer Neighboring gene ReSE screen-validated silencer GRCh37_chr18:34098259-34098446 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:34098790-34099369 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:34099370-34099948 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9405 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13239 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13240 Neighboring gene uncharacterized LOC105372071 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13241 Neighboring gene ReSE screen-validated silencer GRCh37_chr18:34254255-34254481 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr18:34287179-34287680 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13242 Neighboring gene ReSE screen-validated silencer GRCh37_chr18:34349653-34349798 Neighboring gene NANOG hESC enhancer GRCh37_chr18:34367445-34367994 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 13243 Neighboring gene H3K27ac hESC enhancer GRCh37_chr18:34408535-34409327 Neighboring gene tubulin polyglutamylase complex subunit 2 Neighboring gene KIAA1328 Neighboring gene uncharacterized LOC105372069 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr18:34527890-34528524 Neighboring gene uncharacterized LOC124904287

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Intermediate-effect size p.Arg637Gln in FHOD3 increases risk of HCM and is associated with an aggressive phenotype in homozygous carriers. Piqueras-Flores J, et al. J Med Genet, 2024 Apr 19. PMID 38160043
  2. Formin homology 2 domain containing 3 variants associated with hypertrophic cardiomyopathy. Wooten EC, et al. Circ Cardiovasc Genet, 2013 Feb. PMID 23255317, Free PMC Article
  3. Formin Homology 2 Domain Containing 3 (FHOD3) Is a Genetic Basis for Hypertrophic Cardiomyopathy. Ochoa JP, et al. J Am Coll Cardiol, 2018 Nov 13. PMID 30442288
  4. Exome sequencing identifies a FHOD3 p.S527del mutation in a Chinese family with hypertrophic cardiomyopathy. Huang S, et al. J Gene Med, 2020 Mar. PMID 31742804
  5. Deletions of specific exons of FHOD3 detected by next-generation sequencing are associated with hypertrophic cardiomyopathy. Ochoa JP, et al. Clin Genet, 2020 Jul. PMID 32335906

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Intermediate-effect size p.Arg637Gln in FHOD3 increases risk of HCM and is associated with an aggressive phenotype in homozygous carriers.
    Title: Intermediate-effect size p.Arg637Gln in FHOD3 increases risk of HCM and is associated with an aggressive phenotype in homozygous carriers.
  2. A novel splice-site FHOD3 founder variant is a common cause of hypertrophic cardiomyopathy in the population of the Balkans-A cohort study.
    Title: A novel splice-site FHOD3 founder variant is a common cause of hypertrophic cardiomyopathy in the population of the Balkans-A cohort study.
  3. Variant Spectrum of Formin Homology 2 Domain-Containing 3 Gene in Chinese Patients With Hypertrophic Cardiomyopathy.
    Title: Variant Spectrum of Formin Homology 2 Domain-Containing 3 Gene in Chinese Patients With Hypertrophic Cardiomyopathy.
  4. FHOD3 promotes carcinogenesis by regulating RhoA/ROCK1/LIMK1 signaling pathway in medulloblastoma.
    Title: FHOD3 promotes carcinogenesis by regulating RhoA/ROCK1/LIMK1 signaling pathway in medulloblastoma.
  5. Deletions of specific exons of FHOD3 detected by next-generation sequencing are associated with hypertrophic cardiomyopathy.
    Title: Deletions of specific exons of FHOD3 detected by next-generation sequencing are associated with hypertrophic cardiomyopathy.
  6. Exome sequencing identifies a FHOD3 p.S527del mutation in a Chinese family with hypertrophic cardiomyopathy.
    Title: Exome sequencing identifies a FHOD3 p.S527del mutation in a Chinese family with hypertrophic cardiomyopathy.
  7. FHOD3 is a novel disease gene in hypertrophic cardiomyopathy, accounting for approximately 2% of cases.
    Title: Formin Homology 2 Domain Containing 3 (FHOD3) Is a Genetic Basis for Hypertrophic Cardiomyopathy.
  8. These results indicate that RBM20 and PTBP1 play a role in the actin filament functional organization mediated by FHOD3 isoforms and suggest their possible involvement in heart diseases.
    Title: RNA-binding proteins RBM20 and PTBP1 regulate the alternative splicing of FHOD3.
  9. FHOD3 played a role in glioma linear migration.
    Title: Mechanical confinement triggers glioma linear migration dependent on formin FHOD3.
  10. Suggest alpha5beta1/Arp2/Arp3/FHOD3 pathway reprograms the actin cytoskeleton to promote invasive migration and local invasion in vivo.
    Title: α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3.
Submit: New GeneRIF Correction See all GeneRIFs (17)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Cardiomyopathy, familial hypertrophic, 28
MedGen: C5543616 OMIM: 619402 GeneReviews: Not available
not available

EBI GWAS Catalog

Description
Genome-wide association study of periodontal health measured by probing depth in adults ages 18-49 years.
EBI GWAS Catalog
Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs.
EBI GWAS Catalog
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cardiac myofibril assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cortical actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sarcomere organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
FH1/FH2 domain-containing protein 3
Names
formactin-2
formin homolog overexpressed in spleen 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_042837.1 RefSeqGene

    Range
    5018..487525
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001281739.3 → NP_001268668.1  FH1/FH2 domain-containing protein 3 isoform 2

    See identical proteins and their annotated locations for NP_001268668.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks an in-frame coding exon compared to variant 1. The resulting isoform (2) is shorter missing an internal protein segment compared to isoform 1.
    Source sequence(s)
    AB084087, AC090333, AI948493, AK128053, BC081563, HY020952
    Consensus CDS
    CCDS62419.1
    UniProtKB/Swiss-Prot
    A8MQT4, E5F5Q0, Q2V2M9, Q642I2, Q6ZRQ7, Q86TF9, Q8N3A5, Q9C0G8, Q9H604, Q9H6G7
    UniProtKB/TrEMBL
    K7ER94
    Related
    ENSP00000352186.3, ENST00000359247.8
    Conserved Domains (1) summary
    pfam02181
    Location:883 → 1254
    FH2; Formin Homology 2 Domain

  2. NM_001281740.3 → NP_001268669.1  FH1/FH2 domain-containing protein 3 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) contains additional in-frame coding exons compared to variant 1. The resulting longer isoform (3) is muscle-specific and required for the maintenance of myofibrils in heart muscle (PMID:21149568).
    Source sequence(s)
    AC090333, AC131053, AI948493, AK128053, BC031518, BC081563, HM191478, HY020952
    Consensus CDS
    CCDS62418.1
    UniProtKB/Swiss-Prot
    Q2V2M9
    Related
    ENSP00000466937.1, ENST00000590592.6
    Conserved Domains (1) summary
    pfam02181
    Location:1075 → 1446
    FH2; Formin Homology 2 Domain

  3. NM_025135.5 → NP_079411.2  FH1/FH2 domain-containing protein 3 isoform 1

    See identical proteins and their annotated locations for NP_079411.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes isoform 1.
    Source sequence(s)
    AB051482, AC090333, AI948493, AK128053, BC031518, BC081563, HY020952
    Consensus CDS
    CCDS32816.1
    UniProtKB/TrEMBL
    K7ER94
    Related
    ENSP00000257209.3, ENST00000257209.8
    Conserved Domains (1) summary
    pfam02181
    Location:900 → 1271
    FH2; Formin Homology 2 Domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p14 Primary Assembly

    Range
    36297713..36780220
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011526189.2 → XP_011524491.1  FH1/FH2 domain-containing protein 3 isoform X1

    Conserved Domains (1) summary
    pfam02181
    Location:1095 → 1466
    FH2; Formin Homology 2 Domain

  2. XM_011526190.3 → XP_011524492.1  FH1/FH2 domain-containing protein 3 isoform X2

    Conserved Domains (1) summary
    pfam02181
    Location:1095 → 1466
    FH2; Formin Homology 2 Domain

  3. XM_017026008.2 → XP_016881497.1  FH1/FH2 domain-containing protein 3 isoform X15

  4. XM_011526195.2 → XP_011524497.1  FH1/FH2 domain-containing protein 3 isoform X16

    Conserved Domains (1) summary
    pfam02181
    Location:996 → 1367
    FH2; Formin Homology 2 Domain

  5. XM_047437844.1 → XP_047293800.1  FH1/FH2 domain-containing protein 3 isoform X17

  6. XM_047437838.1 → XP_047293794.1  FH1/FH2 domain-containing protein 3 isoform X5

  7. XM_011526192.2 → XP_011524494.1  FH1/FH2 domain-containing protein 3 isoform X3

    Conserved Domains (1) summary
    pfam02181
    Location:1070 → 1441
    FH2; Formin Homology 2 Domain

  8. XM_011526197.2 → XP_011524499.1  FH1/FH2 domain-containing protein 3 isoform X6

    Conserved Domains (1) summary
    pfam02181
    Location:1070 → 1441
    FH2; Formin Homology 2 Domain

  9. XM_047437840.1 → XP_047293796.1  FH1/FH2 domain-containing protein 3 isoform X8

  10. XM_047437841.1 → XP_047293797.1  FH1/FH2 domain-containing protein 3 isoform X9

  11. XM_047437845.1 → XP_047293801.1  FH1/FH2 domain-containing protein 3 isoform X18

  12. XM_047437842.1 → XP_047293798.1  FH1/FH2 domain-containing protein 3 isoform X10

  13. XM_047437846.1 → XP_047293802.1  FH1/FH2 domain-containing protein 3 isoform X19

  14. XM_005258349.2 → XP_005258406.1  FH1/FH2 domain-containing protein 3 isoform X13

    Conserved Domains (1) summary
    pfam02181
    Location:1012 → 1383
    FH2; Formin Homology 2 Domain

  15. XM_011526196.2 → XP_011524498.1  FH1/FH2 domain-containing protein 3 isoform X20

    UniProtKB/TrEMBL
    K7ER94
    Conserved Domains (1) summary
    pfam02181
    Location:920 → 1291
    FH2; Formin Homology 2 Domain

  16. XM_017026009.2 → XP_016881498.1  FH1/FH2 domain-containing protein 3 isoform X22

    UniProtKB/TrEMBL
    K7ER94

  17. XM_047437853.1 → XP_047293809.1  FH1/FH2 domain-containing protein 3 isoform X31

  18. XM_047437854.1 → XP_047293810.1  FH1/FH2 domain-containing protein 3 isoform X32

  19. XM_047437856.1 → XP_047293812.1  FH1/FH2 domain-containing protein 3 isoform X34

  20. XM_047437848.1 → XP_047293804.1  FH1/FH2 domain-containing protein 3 isoform X23

  21. XM_047437855.1 → XP_047293811.1  FH1/FH2 domain-containing protein 3 isoform X33

  22. XM_047437857.1 → XP_047293813.1  FH1/FH2 domain-containing protein 3 isoform X35

  23. XM_047437863.1 → XP_047293819.1  FH1/FH2 domain-containing protein 3 isoform X41

  24. XM_005258354.2 → XP_005258411.1  FH1/FH2 domain-containing protein 3 isoform X25

    UniProtKB/TrEMBL
    K7ER94
    Conserved Domains (1) summary
    pfam02181
    Location:862 → 1233
    FH2; Formin Homology 2 Domain

  25. XM_005258355.3 → XP_005258412.1  FH1/FH2 domain-containing protein 3 isoform X26

    See identical proteins and their annotated locations for XP_005258412.1

    UniProtKB/TrEMBL
    K7ER94
    Conserved Domains (1) summary
    pfam02181
    Location:862 → 1233
    FH2; Formin Homology 2 Domain

  26. XM_047437858.1 → XP_047293814.1  FH1/FH2 domain-containing protein 3 isoform X36

  27. XM_047437860.1 → XP_047293816.1  FH1/FH2 domain-containing protein 3 isoform X38

  28. XM_047437851.1 → XP_047293807.1  FH1/FH2 domain-containing protein 3 isoform X28

  29. XM_047437859.1 → XP_047293815.1  FH1/FH2 domain-containing protein 3 isoform X37

  30. XM_047437861.1 → XP_047293817.1  FH1/FH2 domain-containing protein 3 isoform X39

  31. XM_047437839.1 → XP_047293795.1  FH1/FH2 domain-containing protein 3 isoform X7

  32. XM_047437843.1 → XP_047293799.1  FH1/FH2 domain-containing protein 3 isoform X11

  33. XM_047437849.1 → XP_047293805.1  FH1/FH2 domain-containing protein 3 isoform X24

  34. XM_047437850.1 → XP_047293806.1  FH1/FH2 domain-containing protein 3 isoform X27

  35. XM_047437852.1 → XP_047293808.1  FH1/FH2 domain-containing protein 3 isoform X29

  36. XM_011526193.4 → XP_011524495.1  FH1/FH2 domain-containing protein 3 isoform X4

    Conserved Domains (1) summary
    pfam02181
    Location:1095 → 1466
    FH2; Formin Homology 2 Domain

  37. XM_017026006.3 → XP_016881495.1  FH1/FH2 domain-containing protein 3 isoform X12

  38. XM_017026010.2 → XP_016881499.1  FH1/FH2 domain-containing protein 3 isoform X30

    Conserved Domains (1) summary
    pfam02181
    Location:1017 → 1388
    FH2; Formin Homology 2 Domain

  39. XM_024451268.2 → XP_024307036.1  FH1/FH2 domain-containing protein 3 isoform X21

    UniProtKB/TrEMBL
    K7ER94
    Conserved Domains (2) summary
    pfam02181
    Location:920 → 1291
    FH2; Formin Homology 2 Domain
    cl28033
    Location:156 → 330
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  40. XM_047437862.1 → XP_047293818.1  FH1/FH2 domain-containing protein 3 isoform X40

    Related
    ENSP00000468163.1, ENST00000592930.5

  41. XM_017026007.2 → XP_016881496.1  FH1/FH2 domain-containing protein 3 isoform X14

  42. XM_047437847.1 → XP_047293803.1  FH1/FH2 domain-containing protein 3 isoform X21

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060942.1 Alternate T2T-CHM13v2.0

    Range
    36489301..36973364
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054319163.1 → XP_054175138.1  FH1/FH2 domain-containing protein 3 isoform X1

  2. XM_054319164.1 → XP_054175139.1  FH1/FH2 domain-containing protein 3 isoform X2

  3. XM_054319177.1 → XP_054175152.1  FH1/FH2 domain-containing protein 3 isoform X15

  4. XM_054319178.1 → XP_054175153.1  FH1/FH2 domain-containing protein 3 isoform X16

  5. XM_054319179.1 → XP_054175154.1  FH1/FH2 domain-containing protein 3 isoform X17

  6. XM_054319167.1 → XP_054175142.1  FH1/FH2 domain-containing protein 3 isoform X5

  7. XM_054319165.1 → XP_054175140.1  FH1/FH2 domain-containing protein 3 isoform X3

  8. XM_054319168.1 → XP_054175143.1  FH1/FH2 domain-containing protein 3 isoform X6

  9. XM_054319170.1 → XP_054175145.1  FH1/FH2 domain-containing protein 3 isoform X8

  10. XM_054319171.1 → XP_054175146.1  FH1/FH2 domain-containing protein 3 isoform X9

  11. XM_054319180.1 → XP_054175155.1  FH1/FH2 domain-containing protein 3 isoform X18

  12. XM_054319172.1 → XP_054175147.1  FH1/FH2 domain-containing protein 3 isoform X10

  13. XM_054319181.1 → XP_054175156.1  FH1/FH2 domain-containing protein 3 isoform X19

  14. XM_054319175.1 → XP_054175150.1  FH1/FH2 domain-containing protein 3 isoform X13

  15. XM_054319182.1 → XP_054175157.1  FH1/FH2 domain-containing protein 3 isoform X20

  16. XM_054319185.1 → XP_054175160.1  FH1/FH2 domain-containing protein 3 isoform X22

  17. XM_054319194.1 → XP_054175169.1  FH1/FH2 domain-containing protein 3 isoform X31

  18. XM_054319195.1 → XP_054175170.1  FH1/FH2 domain-containing protein 3 isoform X32

  19. XM_054319197.1 → XP_054175172.1  FH1/FH2 domain-containing protein 3 isoform X34

  20. XM_054319186.1 → XP_054175161.1  FH1/FH2 domain-containing protein 3 isoform X23

  21. XM_054319196.1 → XP_054175171.1  FH1/FH2 domain-containing protein 3 isoform X33

  22. XM_054319198.1 → XP_054175173.1  FH1/FH2 domain-containing protein 3 isoform X35

  23. XM_054319204.1 → XP_054175179.1  FH1/FH2 domain-containing protein 3 isoform X41

  24. XM_054319188.1 → XP_054175163.1  FH1/FH2 domain-containing protein 3 isoform X25

  25. XM_054319189.1 → XP_054175164.1  FH1/FH2 domain-containing protein 3 isoform X26

  26. XM_054319199.1 → XP_054175174.1  FH1/FH2 domain-containing protein 3 isoform X36

  27. XM_054319201.1 → XP_054175176.1  FH1/FH2 domain-containing protein 3 isoform X38

  28. XM_054319191.1 → XP_054175166.1  FH1/FH2 domain-containing protein 3 isoform X28

  29. XM_054319200.1 → XP_054175175.1  FH1/FH2 domain-containing protein 3 isoform X37

  30. XM_054319202.1 → XP_054175177.1  FH1/FH2 domain-containing protein 3 isoform X39

  31. XM_054319169.1 → XP_054175144.1  FH1/FH2 domain-containing protein 3 isoform X7

  32. XM_054319173.1 → XP_054175148.1  FH1/FH2 domain-containing protein 3 isoform X11

  33. XM_054319187.1 → XP_054175162.1  FH1/FH2 domain-containing protein 3 isoform X24

  34. XM_054319190.1 → XP_054175165.1  FH1/FH2 domain-containing protein 3 isoform X27

  35. XM_054319192.1 → XP_054175167.1  FH1/FH2 domain-containing protein 3 isoform X29

  36. XM_054319166.1 → XP_054175141.1  FH1/FH2 domain-containing protein 3 isoform X4

  37. XM_054319174.1 → XP_054175149.1  FH1/FH2 domain-containing protein 3 isoform X12

  38. XM_054319193.1 → XP_054175168.1  FH1/FH2 domain-containing protein 3 isoform X30

  39. XM_054319183.1 → XP_054175158.1  FH1/FH2 domain-containing protein 3 isoform X21

  40. XM_054319203.1 → XP_054175178.1  FH1/FH2 domain-containing protein 3 isoform X40

  41. XM_054319176.1 → XP_054175151.1  FH1/FH2 domain-containing protein 3 isoform X14

  42. XM_054319184.1 → XP_054175159.1  FH1/FH2 domain-containing protein 3 isoform X21

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q2V2M9.2 GenPept UniProtKB/Swiss-Prot:Q2V2M9

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