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cecr2 CECR2 histone acetyl-lysine reader [ Danio rerio (zebrafish) ]

Gene ID: 799918, updated on 2-Nov-2024

Summary

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Official Symbol
cecr2provided by ZNC
Official Full Name
CECR2 histone acetyl-lysine readerprovided by ZNC
Primary source
ZFIN:ZDB-GENE-131121-533
See related
Ensembl:ENSDARG00000078310 AllianceGenome:ZFIN:ZDB-GENE-131121-533
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-276c7.3
Summary
Acts upstream of or within hematopoietic progenitor cell differentiation. Predicted to be part of CERF complex. Orthologous to human CECR2 (CECR2 histone acetyl-lysine reader). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See cecr2 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (16646172..16688534)
105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (16549761..16592134)

Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene ATPase H+ transporting V1 subunit E1a Neighboring gene solute carrier family 25 member 18 Neighboring gene adenosine deaminase 2a Neighboring gene polypeptide N-acetylgalactosaminyltransferase 8a, tandem duplicate 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Efficient identification of CRISPR/Cas9-induced insertions/deletions by direct germline screening in zebrafish. Brocal I, et al. BMC Genomics, 2016 Mar 24. PMID 27009152, Free PMC Article
  2. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within chromatin remodeling IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within hematopoietic progenitor cell differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in single fertilization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of CERF complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of CERF complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
cat eye syndrome critical region protein 2; chromatin remodeling regulator CECR2
Names
cat eye syndrome chromosome region, candidate 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007136.7 Reference GRCz11 Primary Assembly

    Range
    16646172..16688534
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005174362.4 → XP_005174419.1  chromatin remodeling regulator CECR2 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BLL4, F1RCN2
    Related
    ENSDARP00000100992.2, ENSDART00000110426.5
    Conserved Domains (4) summary
    cd05509
    Location:403 → 503
    Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
    pfam09606
    Location:675 → 1110
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam02791
    Location:23 → 63
    DDT; DDT domain
    pfam15346
    Location:202 → 366
    ARGLU; Arginine and glutamate-rich 1

  2. XM_002666820.6 → XP_002666866.3  chromatin remodeling regulator CECR2 isoform X2

    UniProtKB/TrEMBL
    A0A8M1RL92
    Conserved Domains (3) summary
    cd05509
    Location:402 → 502
    Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
    pfam09606
    Location:674 → 1109
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam02791
    Location:23 → 63
    DDT; DDT domain
Nucleotide Protein Strain
Heading Accession and Version

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